Results 31 to 40 of about 62,207 (260)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

How Do Acquired Political Identities Influence Our Neural Processing toward Others within the Context of a Trust Game?

open access: yesFrontiers in Human Neuroscience, 2018
Trust is essential for mutually beneficial human interactions in economic exchange and politics and people’s social identities notably have dramatic effects on trust behaviors toward others.
Chien-Te Wu   +11 more
doaj   +1 more source

Beyond Toxic Masculinity: Reading and Writing Men in Post-Apartheid Namibia

open access: yesAfrica Spectrum, 2023
Over the past few years, the term “toxic masculinity” has entered public debate in Namibia as a way to describe apparently problematic forms of masculine behaviour, particularly in the light of high levels of gender-based violence. Originating in Western
Jack Boulton
doaj   +1 more source

Analytical Study on the Cornering Behavior of an Articulated Tracked Vehicle

open access: yesMachines, 2021
Articulated tracked vehicles have been traditionally studied and appreciated for the extreme maneuverability and mobility flexibility in terms of grade and side slope capabilities. The articulation joint represents an attractive and advantageous solution,
Antonio Tota   +2 more
doaj   +1 more source

Effect of Promotion, Ease of Transaction, and Trust on Purchase Decision of Shopee Pay Later Users

open access: yesPERFORMA, 2022
This research is done with the purpose of analyzing the effect of promotion, ease of transaction, and trust on purchase decision of Shopee Pay Later users as payment method. The cause of doing research towards Shopee Pay Later is there is the increase of Shopee Pay Later users that are influenced by incessant promotion, obstacle when using the account ...
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Zero-Trust Iot Security Architecture for Defence and Public Security Systems

open access: yesScientific Bulletin
The expanding use of Internet of Things (IoT) technologies in defence and public security systems has increased reliance on distributed sensing, edge processing, and real-time decision-support infrastructures.
KARKADAKATTIL Aswin
doaj   +1 more source

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