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Oral toxicities of lauric acid and certain lauric acid derivatives

Toxicology and Applied Pharmacology, 1960
Abstract Subacute toxicity data for lauric acid and sorbitan monclaurate (Span 20) and chronic toxicity data for lauric acid glycerides (S-1062) and polyoxyethylene-20 monolaurate (G-2129) in rats have been presented. Sorbitan monolaurate tested at 25, 20, and 15% levels for 23 weeks caused significant growth depression beginning at the lowest ...
O G, FITZHUGH   +2 more
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Synthesis of 2-monolaurin from pure lauric acid

AIP Conference Proceedings, 2021
An attempt of synthesis 2-monolaurin from lauric acid through trilaurin as an intermediate compound has been successfully conducted. Trilaurin has been afforded via esterification reaction of lauric acid and glycerol with yield and purity of 78 and 84% respectively. Ethanolysis reaction of trilaurin using Lipozyme TL IM enzyme resulted in the formation
Febri Odel Nitbani   +5 more
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Human liver lauric acid hydroxylase activities.

Drug Metabolism and Disposition, 1995
Nine male and five female human liver microsomal sample were examined for laurate 11- and 12-hydroxylase activities. The mean specific activities for the 11- and 12-hydroxylation reactions were 0.78 +/- 0.33 and 1.07 +/- 0.12 nmol/min/mg protein, respectively.
P J, Castle   +4 more
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A degradation study of PLLA containing lauric acid

Biomaterials, 2005
Addition of lauric acid to poly (L-lactide) (PLLA) has resulted in a new family of enhanced degradation biomaterials. Presented is PLLA4.5 (PLLA containing 4.5 wt% lauric acid), the fastest degrading of the family. Degradation was studied via mass changes, gel-permeation chromatography, wide- and small-angle X-ray scattering (WAXS and SAXS ...
Annette C, Renouf-Glauser   +3 more
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Mechanism-based in vivo inactivation of lauric acid hydroxylases

Biochemistry, 1986
The hepatic cytochrome P-450 isozymes that catalyze omega- and (omega - 1)-hydroxylation of lauric acid are specifically inactivated in vitro but not in vivo by 10-undecynoic acid. The lack of in vivo activity may result from rapid degradation of the inhibitor by beta-oxidation.
C A, CaJacob, P R, Ortiz de Montellano
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Degradation of the Lauric acid oils

International Biodeterioration & Biodegradation, 1994
Abstract The composition, properties, uses and degradation of the lauric acid oils have been discussed. Coconut and palm kernel oil contain approximately 40% medium chain fatty acids (C6:0–C12:0). The medium chain fatty acids in these oils are readily degraded by filamentous fungi belonging to the following genera, Penicillium, Aspergillus ...
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The Effect of Diesters and Lauric Acid on Rheological Properties of Air/Water Interfaces Stabilized by Oligofructose Lauric Acid Monoesters

Journal of Agricultural and Food Chemistry, 2013
In this study, the rheological properties of interfaces stabilized by oligofructose fatty acid esters were elucidated. First, the properties of interfaces stabilized by monoesters (ME), diesters (DE), lauric acid (LA), oligofructose (OF), and mixtures of ME with DE, LA, or OF were studied.
van Kempen, S.E.H.J.   +3 more
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Lauric Acid Exhibits Antifungal Activity Against Plant Pathogenic Fungi

Journal of Phytopathology, 2003
AbstractThis study aimed at examining the effects of the saturated fatty acid lauric acid on mycelial growth of Rhizoctonia solani and Pythium ultimum and on infection of barley seedlings with Blumeria graminis f. sp. hordei. Mycelial growth of R. solani and P. ultimum in agar culture was significantly reduced by lauric acid at concentrations of 100 μm
Walters, DR, Walker, RL, Walker, KC
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