Results 91 to 100 of about 25,487 (260)

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source

Dose response association between macrogols, lactulose or other laxatives and colorectal cancer risk.

, 2013
Dose response association between macrogols, lactulose or other laxatives and colorectal cancer risk.
Julia M. Snowball (500440), Rachel A. Charlton (399538), Corinne S. de Vries (113904), Katherine Bloomfield (500441)   +3 more
core   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

The Effects of Prophylactic Laxative Use on Critically Ill Patients Requiring Mechanical Ventilation: A Retrospective Cohort Study

Diseases
Objective: To investigate the effects of prophylactic use of stimulant laxatives and/or docusate on the clinical outcomes in critically ill patients who required mechanical ventilation (MV).
Heqing Tao, Ligang Liu, Weipeng Lu, Ziyan Ni, Xueqing Chen, Milap C. Nahata, Liang Peng   +6 more
doaj   +1 more source

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

Portal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf, Mahboobeh Ebrahimi Varkiani, Saeid Abroun, Pedram Asadi‐Sarabi, Shukoofeh Torabi, Elham Rismani, Mohammad Majd Hammour, Andreas K. Nüssler, Massoud Vosough   +8 more
wiley   +1 more source

Will the Use of Fiber be as Effective as Laxatives in Relieving Constipation in the Geriatric Population? [PDF]

, 2012
OBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of fiber can be as effective as laxatives in relieving constipation in the geriatric population.
Batunkyi, Saunders
core   +1 more source

Preparation regimen is more important than patient-related factors: a randomized trial comparing a standard bowel preparation before colonoscopy with an individualized approach

Romanian Journal of Internal Medicine, 2017
Background. Optimal bowel preparation is one of the most important factors affecting the quality of colonoscopy. Several patient-related factors are known to influence the quality of bowel cleansing but randomized trials in this area are lacking.
Voiosu T., Tanţău Alina, Voiosu A., Benguş Andreea, Mocanu Cristina, Smarandache Bianca, Baicuş C., Vişovan Ioana, Mateescu B.   +8 more
doaj   +1 more source

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

Small, EarlyView.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti   +2 more
wiley   +1 more source

A Systematic Scoping Review of Participant Descriptor, Diversity and Inclusivity Data Reported in Randomised Studies of Post‐Operative Ileus

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Poor reporting of baseline descriptor, diversity and inclusion data is a barrier in surgical research for drawing generalisable conclusions across diverse populations. Post‐operative ileus was used as an exemplar surgical condition to quantify the variation in baseline descriptor, inclusivity and diversity data in randomised ...
Miriam Khalil, Edward Roberts, David G. Jayne, Stephen J. Chapman   +3 more
wiley   +1 more source

Modern approaches to the treatment of constipation in pregnant women

Лечащий Врач
Background. Constipation, or constipation, is a polyetiological pathological condition characterized by prolongation of the intervals between acts of defecation and changes in the shape and consistency of fecal matter.
A. K. Minaeva
doaj   +1 more source