Results 131 to 140 of about 25,828 (235)

Prescription Intervals of Medications for Chronic Use: A Cohort Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Purpose In deprescribing studies, a prescription‐free gap is typically used to determine if patients discontinued their treatment. An appropriate gap depends on the typical time between prescriptions during continued use. This work aims to characterise the interval between prescriptions of chronic drugs (long‐term use) using different methods ...
Ryan Muddiman   +6 more
wiley   +1 more source

Pain Management in Older Adults: An Interprofessional Training Approach Assessed by Script Concordance Tests

open access: yesPain Practice, Volume 26, Issue 8, November 2026.
ABSTRACT Background Optimal perioperative pain management in older adults challenges anesthesiologists due to increased drug sensitivity, altered pharmacokinetics, and limitations of pain assessment tools in cognitively impaired patients. This study evaluated whether a single 60‐min structured collaborative training session between a geriatrician and a
Alexandre Meurant   +4 more
wiley   +1 more source

Hydrophilic Polymers Enable Gastrointestinal Transit Monitoring by Fluorine‐19 Magnetic Resonance Imaging

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
Hydrophilic fluorinated copolymers dissolve in chyme and give a strong, single 19F signal, unlike phase‐separating perfluorocarbons. Combined 1H‐19F MRI tracks their whole‐gut transit non‐invasively and without ionizing radiation. In rats, the tracers move through the gastrointestinal tract, resist resorption, and are well tolerated, a proof‐of‐concept
Ondřej Groborz   +13 more
wiley   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal   +5 more
wiley   +1 more source

Exposome‐wide association study and predictive risk score for incident Alzheimer's disease and related dementias

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Environmental exposures contribute substantially to Alzheimer's disease and related dementias (ADRD), yet comprehensive exposome‐wide investigations systematically evaluating multi‐domain environmental factors remain limited and lacking utility for precision medicine. METHODS We conducted an exposome‐wide association study (ExWAS)
Chenshuang Li   +11 more
wiley   +1 more source

A Case of Remarkable Improvement in Dizziness and Lightheadedness in an Elderly Patient Treated With Goshajinkigan

open access: yes
Traditional &Kampo Medicine, Volume 13, Issue 3, December 2026.
Akiko Kikuchi   +4 more
wiley   +1 more source

Lower Extremity Injuries and Revision Surgery Rates are Increased in Patients With Anorexia Nervosa and Bulimia Nervosa Compared With Controls

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, Volume 8, Issue 5, October 2026.
Purpose To compare lower extremity soft tissue injury and revision surgery rates for patients with anorexia nervosa (AN) and bulimia nervosa (BN) compared with matched controls. Methods This retrospective cohort study used a deidentified claims database.
Jackson G. Woodrow   +7 more
wiley   +1 more source

Ethnomedicinal and Phytopharmaceutical Properties of Syzygium samarangense (Blume) Merr. & L.M. Perry: A Gateway to Future Drug Development

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
ABSTRACT Recently, natural products and plant‐based regimens are widely recognized as potential complementary and alternative therapeutic solutions. Traditionally, ethnomedicinal knowledge, validated through scientific evidence, has been a basis for modern drug discovery, emphasizing the importance of updated phytopharmacological knowledge of medicinal
Sujit Kumar Patro   +3 more
wiley   +1 more source

Osmotic and stimulant laxatives for the management of childhood constipation. [PDF]

open access: yesCochrane Database Syst Rev
Gordon M   +6 more
europepmc   +1 more source

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