Results 191 to 200 of about 47,154 (347)

Studying the Role of Myenteric Amyloidosis in Gastrointestinal Dysmotility and Enteric Neural Dysfunction Using APP/PS1 Mice—Is It an Adequate Animal Model?

open access: yesNeurogastroenterology &Motility, EarlyView.
Amyloidosis in the central and enteric nervous system contributes to cognitive deficits and gastrointestinal dysmotility—the constipation in Alzheimer's disease (AD). APP/PS1 mice, a transgenic mouse model of amyloidosis, recapitulated the amyloidosis in the central nervous system; they were unsustainable in recapitulating the amyloidosis in the ...
Roxanne Fernandes   +8 more
wiley   +1 more source

Drug Survival of Drugs Recommended for Irritable Bowel Syndrome: A Retrospective Observational Study

open access: yesNeurogastroenterology &Motility, EarlyView.
ABSTRACT Background There is limited data on how drugs prescribed for functional bowel disorders are re‐prescribed in clinical practice. This study aimed to investigate drug survival rates of different irritable bowel syndrome (IBS) treatments among patients referred to a gastroenterologist.
Alice Sandberg‐Janzon, Pontus Karling
wiley   +1 more source

Changing Gastrointestinal Transit Time Alters Microbiome Composition and Bile Acid Metabolism: A Cross‐Over Study in Healthy Volunteers

open access: yesNeurogastroenterology &Motility, EarlyView.
Alterations in whole gut transit time (WGTT) significantly impact microbiome composition and bile acid metabolism. Using senna and loperamide, we show that WGTT changes influence bacterial diversity, bile acid profiles, and fibroblast growth factor 19, with effects reversing after 16 days—highlighting the dynamic gut‐microbiome‐bile acid interplay ...
Evette B. M. Hillman   +11 more
wiley   +1 more source

COMPARISON OF LAXATIVE, BEHAVIORAL AND BIOFEEDBACK (TREATMENT OF CHILDHOOD ENCOPRESIS

open access: bronze, 1995
James L. Sutphen   +3 more
openalex   +1 more source

Prolonged Gastrointestinal Transit Times and Dysmotility in m.3243A>G Mitochondrial Disease

open access: yesNeurogastroenterology &Motility, EarlyView.
Carriers of m.3243A>G mitochondrial disease have impaired mitochondrial adenosine triphosphate (ATP) production. Our findings indicate that patients exhibit gastrointestinal dysmotility as assessed by the wireless motility capsule SmartPill. This indicates a critical role of mitochondrial ATP in normal gastrointestinal function.
Simone Rask Nielsen   +6 more
wiley   +1 more source

Prospective Study of Bowel Movement, Laxative Use, and Risk of Colorectal Cancer among Women

open access: bronze, 2000
Laurent Dukas   +5 more
openalex   +1 more source

Adolescent Risk Factors for Adult Pre‐Pregnancy Obesity and High Gestational Weight Gain: A Longitudinal Study

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Risk factors during adolescence appear to shape adult health, but little is known about how they are associated with pregnancy health. Objectives We aimed to assess whether a variety of adolescent risk factors with links to adult overweight or obesity are associated with pre‐pregnancy obesity (Body Mass Index [BMI] ≥ 30 kg/m2) and ...
Susan M. Mason   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy