Results 41 to 50 of about 23,979 (254)

Mechanisms of chronic constipation in children and correction

Медицинский совет, 2013
Chronic constipations represent a heterogeneous group of disorders. They may be a manifestation of irritable bowel syndrome, congenital anomalies (Hirschsprung's disease), or they may be functional, further subdivided into normal or slow transit.
E. A. Kornienko
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

FUNCTIONAL CONSTIPATION, DYNAMICS OF PRESENTATIONS, DIAGNOSTICS, INDIVIDUAL APPROACHES TO THE TREATMENT

Медицинский совет, 2018
The article presents data on functional constipation (FC): the definition (including the one of the last consensus – Rome IV), epidemiology, diagnostics, general approaches to the treatment and the results of using the stimulant drug Slabilen ...
O. N. Minushkin
doaj   +1 more source

Lax additivity

Documenta Mathematica
We introduce notions of lax semiadditive and lax additive (\infty,2) -categories, categorifying the classical notions of semiadditive and additive 1 -categories.
Merlin Christ, Tobias Dyckerhoff, Tashi Walde   +2 more
openaire   +2 more sources

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Laxative overuse in geriatric patients: a growing concern

Journal of the Pakistan Medical Association
Madam, by definition, a laxative is any medicinal substance actively used for treating chronic constipation by softening stools, facilitating their passage, and stimulating bowel movements.
Asma Ashraf, Khushbakht Waqar
doaj   +1 more source

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

British Journal of Clinical Pharmacology, EarlyView.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan, Christian Bach Vase, Christina Mortensen, Liv Andres‐Jensen, Dorte Aalund Olsen, Jonna Skov Madsen, Kjeld Schmiegelow, Rene Mathiasen, Tore Bjerregaard Stage   +8 more
wiley   +1 more source

Dose response association between macrogols, lactulose or other laxatives and colorectal cancer risk. [PDF]

, 2013
Dose response association between macrogols, lactulose or other laxatives and colorectal cancer risk.
Julia M. Snowball (500440), Rachel A. Charlton (399538), Corinne S. de Vries (113904), Katherine Bloomfield (500441)   +3 more
core   +1 more source

MANAGEMENT OF GERIATRIC PATIENTS SUFFERRING FROM CHRONIC CONSTIPATION

Кубанский научный медицинский вестник, 2018
The article discusses diagnosis and differential diagnosis of primary and secondary constipation in elderly patients. The analysis of possible options of constipation treatment is made on the basis of the evidence-based medicine criteria and the use of ...
Yu. S. KOKAREV
doaj   +1 more source