Results 41 to 50 of about 25,487 (260)

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Laxatives Do Not Improve Symptoms of Opioid-Induced Constipation: Results of a Patient Survey [PDF]

, 2016
Introduction.:  Laxatives are commonly used to treat opioid-induced constipation, the commonest and most bothersome complication of opioids. However, laxatives have a nonspecific action and do not target underlying mechanisms of opioid-induced ...
Dickerson, S, McSkimming, P, Emmanuel, A, Johnson, M   +3 more
core   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

MANAGEMENT OF GERIATRIC PATIENTS SUFFERRING FROM CHRONIC CONSTIPATION

Кубанский научный медицинский вестник, 2018
The article discusses diagnosis and differential diagnosis of primary and secondary constipation in elderly patients. The analysis of possible options of constipation treatment is made on the basis of the evidence-based medicine criteria and the use of ...
Yu. S. KOKAREV
doaj   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Modern principles of constipation treatment

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2009
The aim of review. To present up-to-date approach to prescription of laxatives at treatment of constipation.Original positions. The laxatives are agents with the various mode of action.
M. A. Livzan
doaj  

Lower Extremity Injuries and Revision Surgery Rates are Increased in Patients With Anorexia Nervosa and Bulimia Nervosa Compared With Controls

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare lower extremity soft tissue injury and revision surgery rates for patients with anorexia nervosa (AN) and bulimia nervosa (BN) compared with matched controls. Methods This retrospective cohort study used a deidentified claims database.
Jackson G. Woodrow, David G. Deckey, Eugenia Lin, Jack M. Haglin, Joshua S. Bingham, Karan A. Patel, Callie M. Davies, Steven K. Poon   +7 more
wiley   +1 more source

Review article:anthranoid laxatives and their potential carcinogenic effects

, 1999
Anthranoid laxatives are widely used laxatives of natural origin, Because of their chemical structure they are carried unabsorbed to the large bowel, where metabolism to the active aglycones takes place, These aglycones exert their laxative effect by ...
Karrenbeld, A, Kleibeuker, J H, van Gorkom, B A, de Vries, E G; id_orcid   +3 more
core   +1 more source

Tratamento da compactação experimental do cólon maior em eqüinos: resultados de laboratório e exames bioquímicos Treatment of experimental impaction in equine large colon: laboratory findings and biochemical test

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005
Avaliou-se ação da solução isotônica poliônica enteral da sene mais fluidoterapia intravenosa e da fluidoterapia intravenosa no tratamento da compactação no cólon maior em eqüinos. Foram utilizados 20 animais divididos em quatro grupos.
G.E.S. Alves, J.D. Ribeiro Filho, H.P. Oliveira, J.M.G. Abreu   +3 more
doaj   +1 more source

Constipation outcomes in children with and without autism spectrum disorder: Insights from a tertiary motility service. [PDF]

J Pediatr Gastroenterol Nutr
Abstract Objectives Autism spectrum disorder (ASD) is commonly associated with gastrointestinal comorbidities, particularly chronic constipation. Despite high clinical burden and frequent tertiary referrals, comparative data describing clinical characteristics, management and outcomes between children with and without ASD—and across ASD severity levels—
Khalid U, Bolia R, Bunt J, Lang R, Thapar N.   +4 more
europepmc   +2 more sources