Results 31 to 40 of about 25,828 (235)
The article presents data on functional constipation (FC): the definition (including the one of the last consensus – Rome IV), epidemiology, diagnostics, general approaches to the treatment and the results of using the stimulant drug Slabilen ...
O. N. Minushkin
doaj +1 more source
Use of laxatives in institutions for the mentally retarded
Objective: To study, in institutionalized mentally retarded patients, the prevalence of regular laxative use, and to identify its correlates. Methods: Twenty-one of the 22 institutions for the mentally retarded in Flanders (Belgium) provided the setting ...
De Bacquer, Dirk +3 more
core +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Dose response association between macrogols, lactulose or other laxatives and colorectal cancer risk.
Julia M. Snowball (500440) +3 more
core +1 more source
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman +11 more
wiley +1 more source
Laxative overuse in geriatric patients: a growing concern
Madam, by definition, a laxative is any medicinal substance actively used for treating chronic constipation by softening stools, facilitating their passage, and stimulating bowel movements.
Asma Ashraf, Khushbakht Waqar
doaj +1 more source
Paediatric clonidine medication errors: Findings from a multicentre French study
Aims This study aimed to describe the characteristics of medication errors involving clonidine in paediatric patients and reported to French Network of Pharmacovigilance and Poison Control Centres. Methods This retrospective observational study analysed clonidine‐related medication errors reported between 1985 and June 2024 in patients under 12 years ...
Eve‐Marie Thillard +8 more
wiley +1 more source
MANAGEMENT OF GERIATRIC PATIENTS SUFFERRING FROM CHRONIC CONSTIPATION
The article discusses diagnosis and differential diagnosis of primary and secondary constipation in elderly patients. The analysis of possible options of constipation treatment is made on the basis of the evidence-based medicine criteria and the use of ...
Yu. S. KOKAREV
doaj +1 more source
Current Status of Bowel Preparation for Colonoscopy in Japan: A Web-Based Survey of Endoscopists (PRESS Survey). [PDF]
ABSTRACT Objectives The increasing number of patients with colorectal cancer underscores the importance of colonoscopy. Adequate bowel preparation is essential to ensure the quality and safety of colonoscopic examinations; however, data on the current practices in Japan remain limited. This study aimed to clarify the current status of bowel preparation,
Matsumoto T +8 more
europepmc +2 more sources
Dietary Artificial Sweeteners: From Chemical Transformation in Food to Gut Microbial Processing
This review article unites classical and recent findings on the stability of artificial sweeteners in food. The focus is on ten sweeteners approved in the European Union: their chemical stability during processing and storage, individual degradation products, and their interactions with the intestinal microbiota.
Jürgen Lassak, Michael Hellwig
wiley +1 more source

