Results 11 to 20 of about 4,599,256 (278)

Modulator property of the intrinsic cortical projection from layer 6 to layer 4 [PDF]

open access: yesFrontiers in Systems Neuroscience, 2009
Layer 4 of the sensory neocortex receives widespread convergent inputs from thalamic, intracortical, and corticocortical sources. Yet, the relative information bearing roles for most of these pathways remain largely undefined.
Charles C Lee, S. M Sherman
doaj   +3 more sources

Somatosensory control of thalamic relay neurons is regulated by two distinct layer 6 feedback systems [PDF]

open access: yesiScience
Summary: The medial posterior (POm) and ventral posterior medial (VPM) thalamic nuclei sort and filter somatosensory information that is sent to the primary somatosensory cortex (S1). Corticothalamic feedback from distinct cell populations of S1 layer 6 (
Josephine Ansorge   +1 more
doaj   +2 more sources

A consensus definition for deep layer 6 excitatory neurons in mouse somatosensory, visual, and motor cortex [PDF]

open access: yesCell Reports
Summary: To understand neocortical function, it is helpful to define cortical cell types. Recent studies indicate that neurons in the deepest cortical layer play roles in mediating thalamocortical interactions and modulating brain state and are ...
Su-Jeong Kim   +20 more
doaj   +2 more sources

Layer-Specific Inhibitory Microcircuits of Layer 6 Interneurons in Rat Prefrontal Cortex. [PDF]

open access: yesCereb Cortex, 2021
Abstract GABAergic interneurons in different cortical areas play important roles in diverse higher-order cognitive functions. The heterogeneity of interneurons is well characterized in different sensory cortices, in particular in primary somatosensory and visual cortex.
Ding C   +3 more
europepmc   +9 more sources

Functional Clusters of Neurons in Layer 6 of Macaque V1. [PDF]

open access: yesJ Neurosci, 2020
Layer 6 appears to perform a very important role in the function of macaque primary visual cortex, V1, but not enough is understood about the functional characteristics of neurons in the layer 6 population. It is unclear to what extent the population is homogeneous with respect to their visual properties or if one can identify ...
Hawken MJ   +10 more
europepmc   +4 more sources

Layer 6 corticothalamic neurons activate a cortical output layer, layer 5a. [PDF]

open access: yesJ Neurosci, 2014
Layer 6 corticothalamic neurons are thought to modulate incoming sensory information via their intracortical axons targeting the major thalamorecipient layer of the neocortex, layer 4, and via their long-range feedback projections to primary sensory thalamic nuclei.
Kim J   +4 more
europepmc   +4 more sources

Intracortical convergence of layer 6 neurons. [PDF]

open access: yesNeuroreport, 2012
Axonal branches from a subset of neurons in cerebral cortical layer 6 innervate both cortical layer 4 and the thalamus. As such, these neurons are poised to modulate thalamocortical transmission at multiple forebrain sites. Here, we examined the functional organization of the layer 6 intracortical projections in auditory, somatosensory, and visual ...
Lee CC, Lam YW, Sherman SM.
europepmc   +4 more sources

Developing Machine Learning Algorithms on Routinely Collected Administrative Health Data - Lessons from Ontario, Canada.

open access: yesInternational Journal of Population Data Science, 2022
There has been considerable growth in the development of machine learning models for clinical applications; however, less attention has been paid to applications at the health systems level.
Vinyas Harish   +10 more
doaj   +1 more source

Decentralized federated learning through proxy model sharing

open access: yesNature Communications, 2023
Institutions in highly regulated domains such as finance and healthcare often have restrictive rules around data sharing. Federated learning is a distributed learning framework that enables multi-institutional collaborations on decentralized data with ...
Shivam Kalra   +4 more
doaj   +1 more source

Predicting adverse outcomes due to diabetes complications with machine learning using administrative health data

open access: yesnpj Digital Medicine, 2021
Across jurisdictions, government and health insurance providers hold a large amount of data from patient interactions with the healthcare system.
Mathieu Ravaut   +10 more
doaj   +1 more source

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