Results 21 to 30 of about 1,817 (168)

Oxidative and Inflammatory Mechanisms Induced by Intermittent Hypoxia Leading to Vascular Alterations in Rodents: A Systematic Review and Meta-Analysis. [PDF]

Oxid Med Cell Longev
Objectives Obstructive sleep apnea (OSA) and the related intermittent hypoxia (IH) are recognized as major cardiovascular risk factors. In a previous meta‐analysis, we confirmed the impact of IH on structural and functional remodeling of vessels in rodent models of IH.
Reveyaz MA, Peyronnel C, Boëte Q, Fournier J, Arnaud C, Belaïdi E, Harki O, Pépin JL, Khouri C, Faury G, Briançon-Marjollet A.   +10 more
europepmc   +2 more sources

Rhodamine6G and Hœchst33342 narrow BmrA conformational spectrum for a more efficient use of ATP [PDF]

Nature Communications
Multidrug ABC transporters harness the energy of ATP binding and hydrolysis to translocate substrates out of the cell and detoxify them. While this involves a well-accepted alternating access mechanism, molecular details of this interplay are still ...
A. Gobet, L. Moissonnier, E. Zarkadas, S. Magnard, E. Bettler, J. Martin, R. Terreux, G. Schoehn, C. Orelle, JM Jault, P. Falson, V. Chaptal   +11 more
doaj   +2 more sources

Hierarchical Poromechanical Approach to Investigate the Impact of Mechanical Loading on Human Skin Micro-Circulation. [PDF]

Int J Numer Method Biomed Eng
A hierarchical poromechanical theory was developed to model human skin, separately accounting for interstitial fluid and cell characteristic times. Implemented in FEniCSx, it was validated through laser Doppler flowmetry experiments. To ensure transparency, all data and codes are publicly available on GitHub, combining theory, numerical validation, and
Lavigne T, Urcun S, Fromy B, Josset-Lamaugarny A, Lagache A, Suarez-Afanador CA, Bordas SPA, Rohan PY, Sciumè G.   +8 more
europepmc   +2 more sources

Objective diagnosis of internal nasal valve collapse by four-phase rhinomanometry. [PDF]

Laryngoscope Investig Otolaryngol, 2022
Abstract Background Internal valve collapse is a frequent cause of nasal obstruction but remains poorly understood and is sometimes treated inappropriately as a result. No functional or imaging test for the condition has been validated and the reference diagnostic technique is physical examination.
Gagnieur P, Fieux M, Louis B, Béquignon E, Bartier S, Vertu-Ciolino D.   +5 more
europepmc   +2 more sources

Thermal infrared imaging with LBTI's LMIRCAM and NOMIC [PDF]

SPIE Proceedings, 2020
The Large Binocular Telescope Interferometer (LBTI) is a NASA-funded instrument of the LBT designed for high-sensitivity, high-contrast, and high-resolution infrared (1.5-13 ?m) imaging. To carry out a wide range of high-spatial resolution observations, it can combine the two AO-corrected 8.4-m apertures of the LBT in various ways including direct (non-
Hinz, P. M., Defrere, Denis, Skemer, A., Bailey, V., Stone, J., Spalding, E., Vaz, A., Pinna, E., Puglisi, A., Esposito, S., Montoya, M., Downey, E., Leisenring, J., Durney, O., Hoffmann, W., Hill, J., Millan-Gabet, R., Mennesson, B., Danchi, W., Morzinski, K., Grenz, P., Skrutskie, M., Ertel, S.   +22 more
openaire   +4 more sources

MiR-30a-5p Alters Epidermal Terminal Differentiation during Aging by Regulating BNIP3L/NIX-Dependent Mitophagy

Cells, 2022
Chronological aging is characterized by an alteration in the genes’ regulatory network. In human skin, epidermal keratinocytes fail to differentiate properly with aging, leading to the weakening of the epidermal function.
Fabien P. Chevalier, Julie Rorteau, Sandra Ferraro, Lisa S. Martin, Alejandro Gonzalez-Torres, Aurore Berthier, Naima El Kholti, Jérôme Lamartine   +7 more
doaj   +1 more source

Synthetic injectable and porous hydrogels for the formation of skeletal muscle fibers: Novel perspectives for the acellular repair of substantial volumetric muscle loss [PDF]

Journal of Tissue Engineering
In severe skeletal muscle damage, muscle tissue regeneration process has to face the loss of resident muscle stem cells (MuSCs) and the lack of connective tissue necessary to guide the regeneration process.
Louise Griveau, Marion Bouvet, Emilie Christin, Cloé Paret, Lauriane Lecoq, Sylvie Radix, Thomas Laumonier, Jerome Sohier, Vincent Gache   +8 more
doaj   +2 more sources

Velhice LGBTI e Comunidade Rural Litorânea: um estudo das representações sociais entre uma população majoritariamente católica

Psicología, Conocimiento y Sociedad, 2023
Esse estudo teve como objetivo identificar e compreender as representações sociais da velhice LGBTI entre pessoas adultas de uma comunidade rural litorânea. Contou-se com a participação de 31 pessoas, majoritariamente mulheres (65%), heterossexuais (97%),
Evair Mendes da Silva Sousa, Mateus Egilson da Silva Alves, Ludgleydson Fernandes de Araújo, Igor Eduardo de Lima Bezerra, Maria Fernanda Lima Silva, Ana Gabriela Aguiar Trévia Salgado   +5 more
doaj   +1 more source

Procollagen C-proteinase enhancer-1 (PCPE-1), a potential biomarker and therapeutic target for fibrosis

Matrix Biology Plus, 2021
The correct balance between collagen synthesis and degradation is essential for almost every aspect of life, from development to healthy aging, reproduction and wound healing.
Priscillia Lagoutte, Emmanuel Bettler, Sandrine Vadon-Le Goff, Catherine Moali   +3 more
doaj   +1 more source

Impaired microvascular function in patients with sickle cell anemia and leg ulcers improved with healing. [PDF]

Br J Haematol
Summary Leg Ulcer (LU) pathophysiology is still not well understood in sickle cell anaemia (SCA). We hypothesised that SCA patients with LU would be characterised by lower microvascular reactivity. The aim of the present study was to compare the microcirculatory function (transcutaneous oxygen pressure (TcPO2) on the foot and laser Doppler flowmetry on
Catella J, Turpin E, Connes P, Nader E, Carin R, Martin M, Rezigue H, Nougier C, Dargaud Y, Josset-Lamaugarny A, Dugrain J, Marano M, Leuci A, Boisson C, Renoux C, Joly P, Poutrel S, Hot A, Guillot N, Fromy B.   +19 more
europepmc   +2 more sources