Results 61 to 70 of about 403 (140)
Thermal Infrared Imaging of Protoplanetary Disks and Substellar Companions with LBTI
The ESO/Breakthrough-sponsored New Earths in the Alpha Centauri Region (NEAR) program recently completed the first ultra-deep stare on Alpha Centauri with the upgraded VISIR-NEAR instrument. In this talk, I will describe the data reduction and scientific results of the NEAR campaign, with a focus on challenges within the existing data and how ...
openaire +1 more source
Abstract Since volcanic activity was first discovered on Io from Voyager images in 1979, changes on Io's surface have been monitored from both spacecraft and ground‐based telescopes. Here, we present the highest spatial resolution images of Io ever obtained from a ground‐based telescope.
Al Conrad +20 more
wiley +1 more source
Micelle-Based Adjuvants for Subunit Vaccine Delivery
In the development of subunit vaccines with purified or recombinant antigens for cancer and infectious diseases, the design of improved and safe adjuvants able to efficiently target the antigen presenting cells, such as dendritic cells, represents a ...
Thomas Trimaille, Bernard Verrier
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ELT Imaging of MWC 297 from the 23 m LBTI: Complex Disk Structure and a Companion Candidate
Abstract Herbig Ae/Be stars represent the early outcomes of star formation and the initial stages of planet formation at intermediate stellar masses. Understanding both of these processes requires detailed characterization of their disk structures and companion frequencies. We present new 3.7 μm imaging of the Herbig Be star MWC 297 from
S. Sallum +5 more
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Inhibitors of BMP‐1/tolloid‐like proteinases: efficacy, selectivity and cellular toxicity
BMP‐1/tolloid‐like proteinases belong to the astacin family of human metalloproteinases, together with meprins and ovastacin. They represent promising targets to treat or prevent a wide range of diseases such as fibrotic disorders or cancer. However, the
Maya Talantikite +8 more
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Recent Developments in Layer‐by‐Layer Assembly for Drug Delivery and Tissue Engineering Applications
Layer‐by‐layer (LbL) films represent a powerful approach for surface functionalization and for the production of free‐standing objects. This article reviews recent applications in drug delivery and tissue engineering, coming closer to clinical applications.
João Borges +16 more
wiley +1 more source
Abstract Aim We tested the hypothesis that low testosterone alters the effects of intermittent hypoxia (IH) on glucose homeostasis, hepatic oxidative stress, and transcriptomic profile in male mice. Methods We used sham‐operated or orchiectomized (ORX) mice exposed to normoxia (Nx) or IH for 2 weeks.
Gauthier Ganouna‐Cohen +8 more
wiley +1 more source
Histones deacetylases in the epidermis: structure, functions and therapeutic implications
Histone deacetylases (HDACs) are key epigenetic regulators that catalyze the removal of acetyl groups from histones and non-histone proteins, thereby modulating chromatin accessibility and gene expression.
Chloé Nguyen Van, Jérôme Lamartine
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Abstract Background Skin wound healing is a complex mechanism which requires a lot of energy, mainly provided by mitochondrial respiration. However, little is known about the mitochondrial bioenergetics of mice skin. We sought to develop a microplate‐based assay to directly measure oxygen consumption in whole mice skin with the goal of identifying ...
Justine Dugrain +4 more
wiley +1 more source
Abstract Introduction Recent studies report that latent tuberculosis infection (LTBI) may lead to an increased risk of cardiovascular disease (CVD) that led us to hypothesize that LTBI may play an important role in major adverse cardiovascular events (MACE) in dialysis patients. Methods A single‐center retrospective cohort study was conducted.
Yun Xia +6 more
wiley +1 more source

