Results 61 to 70 of about 403 (140)

Thermal Infrared Imaging of Protoplanetary Disks and Substellar Companions with LBTI

open access: yes, 2020
The ESO/Breakthrough-sponsored New Earths in the Alpha Centauri Region (NEAR) program recently completed the first ultra-deep stare on Alpha Centauri with the upgraded VISIR-NEAR instrument. In this talk, I will describe the data reduction and scientific results of the NEAR campaign, with a focus on challenges within the existing data and how ...
openaire   +1 more source

Observation of Io's Resurfacing via Plume Deposition Using Ground‐Based Adaptive Optics at Visible Wavelengths With LBT SHARK‐VIS

open access: yesGeophysical Research Letters, Volume 51, Issue 11, 16 June 2024.
Abstract Since volcanic activity was first discovered on Io from Voyager images in 1979, changes on Io's surface have been monitored from both spacecraft and ground‐based telescopes. Here, we present the highest spatial resolution images of Io ever obtained from a ground‐based telescope.
Al Conrad   +20 more
wiley   +1 more source

Micelle-Based Adjuvants for Subunit Vaccine Delivery

open access: yesVaccines, 2015
In the development of subunit vaccines with purified or recombinant antigens for cancer and infectious diseases, the design of improved and safe adjuvants able to efficiently target the antigen presenting cells, such as dendritic cells, represents a ...
Thomas Trimaille, Bernard Verrier
doaj   +1 more source

ELT Imaging of MWC 297 from the 23 m LBTI: Complex Disk Structure and a Companion Candidate

open access: yesThe Astronomical Journal, 2020
Abstract Herbig Ae/Be stars represent the early outcomes of star formation and the initial stages of planet formation at intermediate stellar masses. Understanding both of these processes requires detailed characterization of their disk structures and companion frequencies. We present new 3.7 μm imaging of the Herbig Be star MWC 297 from
S. Sallum   +5 more
openaire   +2 more sources

Inhibitors of BMP‐1/tolloid‐like proteinases: efficacy, selectivity and cellular toxicity

open access: yesFEBS Open Bio, 2018
BMP‐1/tolloid‐like proteinases belong to the astacin family of human metalloproteinases, together with meprins and ovastacin. They represent promising targets to treat or prevent a wide range of diseases such as fibrotic disorders or cancer. However, the
Maya Talantikite   +8 more
doaj   +1 more source

Recent Developments in Layer‐by‐Layer Assembly for Drug Delivery and Tissue Engineering Applications

open access: yesAdvanced Healthcare Materials, Volume 13, Issue 8, March 25, 2024.
Layer‐by‐layer (LbL) films represent a powerful approach for surface functionalization and for the production of free‐standing objects. This article reviews recent applications in drug delivery and tissue engineering, coming closer to clinical applications.
João Borges   +16 more
wiley   +1 more source

Loss of testosterone induces postprandial insulin resistance and increases the expression of the hepatic antioxidant flavin‐containing monooxygenases in mice exposed to intermittent hypoxia

open access: yesActa Physiologica, Volume 240, Issue 3, March 2024.
Abstract Aim We tested the hypothesis that low testosterone alters the effects of intermittent hypoxia (IH) on glucose homeostasis, hepatic oxidative stress, and transcriptomic profile in male mice. Methods We used sham‐operated or orchiectomized (ORX) mice exposed to normoxia (Nx) or IH for 2 weeks.
Gauthier Ganouna‐Cohen   +8 more
wiley   +1 more source

Histones deacetylases in the epidermis: structure, functions and therapeutic implications

open access: yesFrontiers in Epigenetics and Epigenomics
Histone deacetylases (HDACs) are key epigenetic regulators that catalyze the removal of acetyl groups from histones and non-histone proteins, thereby modulating chromatin accessibility and gene expression.
Chloé Nguyen Van, Jérôme Lamartine
doaj   +1 more source

Exploring mitochondrial metabolism of wild‐type and diabetic mice skin explants using the Seahorse technology

open access: yesSkin Research and Technology, Volume 30, Issue 3, March 2024.
Abstract Background Skin wound healing is a complex mechanism which requires a lot of energy, mainly provided by mitochondrial respiration. However, little is known about the mitochondrial bioenergetics of mice skin. We sought to develop a microplate‐based assay to directly measure oxygen consumption in whole mice skin with the goal of identifying ...
Justine Dugrain   +4 more
wiley   +1 more source

Risk factors and prognosis for latent tuberculosis infection in dialysis patients: A retrospective cohort study at a single tertiary care center

open access: yesSeminars in Dialysis, Volume 37, Issue 1, Page 59-64, January/February 2024.
Abstract Introduction Recent studies report that latent tuberculosis infection (LTBI) may lead to an increased risk of cardiovascular disease (CVD) that led us to hypothesize that LTBI may play an important role in major adverse cardiovascular events (MACE) in dialysis patients. Methods A single‐center retrospective cohort study was conducted.
Yun Xia   +6 more
wiley   +1 more source

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