Results 101 to 110 of about 21,610 (241)

Exploring the Fragmentation of Sodiated Species Involving Covalent‐Bond Cleavages for Metabolite Characterization

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Electrospray (ESI), the most popular desorption/ionization technique used in mass spectrometry‐based metabolomics, generates both protonated and deprotonated molecules, as well as adduct ions, sodium being the most frequent monoatomic cation entering their composition.
Annelaure Damont   +9 more
wiley   +1 more source

Toxicant early-life exposure: A mini review of the comprehensive LC-MS/MS analysis of xenobiotics in breast milk samples

open access: yesTạp chí Kiểm nghiệm và An toàn thực phẩm
The analysis of xenobiotics in breast milk is crucial for understanding the impact of early-life exposure on infant health. This mini-review highlights some recent advancements in mass spectrometry, focusing on SCIEX MS systems, to detect and quantify a ...
Si-Hung Le
doaj   +1 more source

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

open access: yesVIEW, EarlyView.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu   +7 more
wiley   +1 more source

The receptor‐like pseudokinase LENG stimulates chilling tolerance in rice by inhibiting the activity of the OsCRPK1‐OsGF14d module

open access: yesJournal of Integrative Plant Biology, EarlyView.
The rice receptor‐like pseudokinase LENG enhances chilling tolerance by binding to and suppressing the kinase activity of OsCRPK1, thereby preventing OsCRPK1‐mediated phosphorylation of the cold‐tolerance positive regulator OsGF14d. ABSTRACT Cold damage during the seedling and reproductive stages has a pronounced impact on rice development and yield ...
Shuting Yuan   +12 more
wiley   +1 more source

Kvantitativ analyse av kortisol og kortison ved LC-HRMS i Atlantisk laks (Salmo salar), og sammenlikning av analysedata mellom LC-HRMS og ELISA

open access: yes, 2022
Oppdrett av Atlantisk laks (Salmo salar) har lenge vært en stor og viktig næring i norsk økonomi. Oppdrettsindustrien har i lengre tid opplevd problemer med ulike sykdommer som medført høy dødelighet. I den siste tiden har også fokuset på god fiskevelferd og bærekraft økt.
openaire   +1 more source

Effect of Linaclotide on Colonic Motility Assessed With Intraluminal Colonic High‐Resolution Manometry in Healthy Subjects. An Acute, Open Label, Randomized, Crossover, Reader‐Blinded Study

open access: yesNeurogastroenterology &Motility, EarlyView.
Our study showed that, in healthy controls, acute administration of linaclotide increased the total number of long‐distance propagating and the pre‐prandial pancolonic pressurizations. Further studies need to address whether the observed effects are directly or indirectly mediated by the mechanism of action of this useful medication to treat chronic ...
Christian Lambiase   +7 more
wiley   +1 more source

Dehydration‐driven organization of metabolites into NaDES‐like assemblies in orthodox seeds

open access: yesNew Phytologist, EarlyView.
Summary Desiccation tolerance in plants, especially during orthodox seed dehydration, relies on compatible solute accumulation, complex molecular mechanisms, and intermolecular organizations that remain poorly understood. We combined metabolite profiling, mass spectrometry imaging, and electrospray and cold‐spray ionization mass spectrometry to ...
Youcef Haddad   +11 more
wiley   +1 more source

Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao   +7 more
wiley   +1 more source

Atmospheric Deposition of Organic Pollutants: A Comprehensive Review of Sampling and Analytical Methodologies

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Atmospheric deposition of organic pollutants plays a crucial role in the transport and fate of contaminants in the environment, with implications for ecosystem health and human exposure. Persistent organic pollutants (POPs), polycyclic aromatic hydrocarbons (PAHs) and microplastics are increasingly recognized as transboundary threats due to ...
Iva Smoljo   +2 more
wiley   +1 more source

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