Results 141 to 150 of about 21,610 (241)

Combination of GC-IMS and Nano-LC/HRMS Reveals the Mechanism of Superheated Steam Glycosylation Modification in Improving Oyster Peptide Flavor. [PDF]

Foods
Wang LH, Zhang JW, Tu ZC, Sha XM, Huang YY, Hu ZZ.   +5 more
europepmc   +1 more source

Chromones as Nonclassical Inhibitors of Carbonic Anhydrase IX and XII Isoforms: Probing Chromone‐Based Derivatives

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
Chromone‐based derivatives were synthesized and evaluated for selective inhibition of tumor‐associated carbonic anhydrases IX and XII. Structure–activity relationships, docking studies, and ADMET profiling revealed promising candidates with selective tumoral isoform inhibition, supporting their potential as anticancer leads. ABSTRACT A small library of
Lisa Sequeira, Simona Distinto, Carlos Fernandes, Erica Sanna, Rita Meleddu, Marco Gaspari, Filippo Cottiglia, Alessia Onali, Andrea Angeli, Fernanda Borges, Eugenio Uriarte, Stefano Alcaro, Claudiu T. Supuran, Elias Maccioni   +13 more
wiley   +1 more source

Separation and Identification of Impurity of Chlortetracycline Hydrochloride Not Included in the European Pharmacopoeia

Biomedical Chromatography, Volume 40, Issue 3, March 2026.
ABSTRACT Drug impurities can affect the clinical efficacy of medicines and may even present substantial health risks. Consequently, the regulation and investigation of such impurities are critically important. In this study, we observed that the chemical structure of impurity E in chlortetracycline hydrochloride, as described in the European ...
Xi Chen, Jun Meng
wiley   +1 more source

In silico and in vitro antibacterial evaluation of eight Anatolian Salvia species with chemical profiling by LC-HRMS. [PDF]

Sci Rep
Yazıcı-Tütüniş S, Alim Toraman GÖ, Dincel ED, Tufan S, Akalın E, Tan E, Ulusoy-Güzeldemirci N, Gören AC, Miski M, Topçu G, Tan N.   +10 more
europepmc   +1 more source

Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision Framework

Clinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 591-597, March 2026.
Radiolabeled human mass balance studies are crucial for identifying circulating metabolites and understanding drug absorption, excretion, and clearance pathways. Metabolite profiling involves quantifying all drug‐related entities, including parent drug and metabolites in plasma and excreta, using extended liquid chromatography methods coupled with ...
Filip Cuyckens, Wenying Li, Adam M. Auclair, Kenneth C. Cassidy, Cathy Cantalloube, Gary Collins, Alexander D. James, Chris Gibson, Ulrike Glaenzel, Felix Huth, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Pietro Brunetti, Hanno Schieferstein, David Wagner, Gregory S. Walker, Shuai Wang, Qin Yue, Jason Boer, Cyrus Khojasteh   +21 more
wiley   +1 more source

Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering. [PDF]

Environ Sci Technol
Haalck I, Krauss M, Brack W, Huber C.
europepmc   +1 more source

Cannabichromene variation in hemp cultivars

Crop Science, Volume 66, Issue 2, March/April 2026.
Abstract Cannabichromene (CBC) is a nonpsychoactive cannabinoid with pharmaceutical potential that is attracting significant interest for its potential therapeutic applications. However, the factors governing CBC production in Cannabis sativa remain largely unknown. This study aimed to investigate the variation in CBC accumulation within different Type
Anthony Torres, Caleb King, Christopher S. Pauli, Thomas Blank, Donald P. Land, Kymron DeCesare, Reggie Gaudino   +6 more
wiley   +1 more source

Diversity and Social Sustainability: A Systematic Review and Integrative Framework for Advancing Socially Sustainable Diversity Management

Corporate Social Responsibility and Environmental Management, Volume 33, Issue 2, Page 2949-2970, March 2026.
ABSTRACT Diversity is essential for social sustainability, yet its role in advancing social sustainability remains underexplored. This systematic and integrative review aims to integrate diversity literature with social sustainability and two key processes driving organisational sustainability—CSR and sustainable HRM. Drawing on 461 papers across three
Claudia Díaz‐Leyva, Rosalía Cascón‐Pereira   +1 more
wiley   +1 more source

Active Learning Improves Ionization Efficiency Predictions and Quantification in Nontargeted LC/HRMS. [PDF]

Anal Chem
Wang WC, Amini N, Huber C, Kull M, Kruve A.   +4 more
europepmc   +1 more source

Identification and Structural Elucidation of a New Synthetic Cannabinoid, MDMB‐5′Br‐PINACA, in Seized Herbal Materials

Drug Testing and Analysis, Volume 18, Issue 3, Page 334-340, March 2026.
MDMB‐5Br‐PINACA, a novel synthetic cannabinoid, was identified and structurally characterized in seized herbal products using GC‐MS, LC‐HRMS, and NMR. The discovery underscores ongoing diversification of SCs and the need for vigilant surveillance.
Alexandre Barcia de Godoi, Lucas André Zeoly, Rafael Lanaro, Ingrid Simões Oliveira, Mariana Cepollaro Diana, Mauricio Yonamine, Jose Luiz Costa   +6 more
wiley   +1 more source