Results 31 to 40 of about 60,310 (255)
Antioxidants, 2022 This study aimed to assess and correlate the phenolic content and the antioxidant activity of the methanol extracts of the stems, roots, flowers, and leaves of Echinops spinosus L. from north-eastern Algeria.
Amel Bouzabata +8 more
doaj +1 more source
Emerging ContaminantsA targeted method for the quantitative determination of PFAS residues in fish feed and marine aquaculture fish species was developed and validated in the current study.
Ourania Koloka +4 more
doaj +1 more source
High Resolution Mass Spectrometry Fragmentation Rules of Etomidate and Its Structural Analogues
Fayixue ZazhiObjectiveTo explore the characteristic fragment ions, ion abundance ratios and mass spectrometry fragmentation rules of etomidate and its structural analogues by using gas chromatography-quadrupole/orbitrap mass spectrometry （GC-Q/Orbitrap MS） and liquid
FAN Xian-yu +4 more
doaj +1 more source
International Journal of Analytical Chemistry, 2021 Potentilla freyniana Bornm. (P. freyniana), belonging to the family Rosaceae, has been used as a folk medicine in China. However, as we know, the constituents and the systematic elucidation of the mechanism were not fully investigated.
Wei Cai +6 more
doaj +1 more source
Datasets from label-free quantitative proteomic analysis of human glomeruli with sclerotic lesions
Data in Brief, 2015 Human glomeruli with intermediate (i-GS) and advanced (GS) sclerotic lesions as well as the normal control (Nor) were captured from laser microdissection, digested by trypsin and subjected to shotgun LC-MS/MS analysis (LTQ-Orbitrap XL).
Ying Zhang +8 more
doaj +1 more source
MS2CNN: predicting MS/MS spectrum based on protein sequence using deep convolutional neural networks
BMC Genomics, 2019 Background Tandem mass spectrometry allows biologists to identify and quantify protein samples in the form of digested peptide sequences. When performing peptide identification, spectral library search is more sensitive than traditional database search ...
Yang-Ming Lin +2 more
doaj +1 more source
Signature Ions in MS/MS Spectra for Dansyl-Aminohexyl-QQIV Adducts on Lysine
Molecules, 2020 Bacterial transglutaminase was used to label human plasma proteins with fluorescent tags. Protein lysines were modified with dansyl-epsilon-aminohexyl-Gln-Gln-Ile-Val-OH (dansylQQIV), while protein glutamines were modified with dansyl cadaverine. Labeled
Lawrence M. Schopfer, Oksana Lockridge
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Multistage Detection of Tetrodotoxin Traces in Diodon hystrix Collected in El Salvador
Toxins, 2023 This study describes a multistage methodology to detect minute amounts of tetrodotoxin in fishes, a plan that may be broadened to include other marine organisms. This methodology was applied to porcupinefish (Diodon hystrix) collected in Punta Chiquirín,
Juan Carlos Fuentes-Monteverde +5 more
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source