Results 51 to 60 of about 313,222 (315)

MS2CNN: predicting MS/MS spectrum based on protein sequence using deep convolutional neural networks

BMC Genomics, 2019
Background Tandem mass spectrometry allows biologists to identify and quantify protein samples in the form of digested peptide sequences. When performing peptide identification, spectral library search is more sensitive than traditional database search ...
Yang-Ming Lin, Ching-Tai Chen, Jia-Ming Chang   +2 more
doaj   +1 more source

Rapid Identification and Systematic Mechanism of Flavonoids from Potentilla freyniana Bornm. Based on UHPLC-Q-Exactive Orbitrap Mass Spectrometry and Network Pharmacology

International Journal of Analytical Chemistry, 2021
Potentilla freyniana Bornm. (P. freyniana), belonging to the family Rosaceae, has been used as a folk medicine in China. However, as we know, the constituents and the systematic elucidation of the mechanism were not fully investigated.
Wei Cai, Kailin Li, Shihan Qin, Pei Xiong, Jie Peng, Silin Shi, Zaiqi Zhang   +6 more
doaj   +1 more source

Proteins interacting with DmHsp22 by orbitrap fusion LC-MS/MS mass spectrometer.

, 2018
Proteins interacting with DmHsp22 by orbitrap fusion LC-MS/MS mass spectrometer.
Nicolas Pichaud (3258165), Robert M. Tanguay (251667), Etienne Hebert Chatelain (4915630), Geneviève Morrow (3126870), Yasmine Ould Amer (4915624), Afrooz Dabbaghizadeh (4915627)   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Polyphenolic profiling of Euphorbia cardiophylla, an endemic Turkish species, using Liquid chromatography-High resolution Orbitrap mass spectrometry and investigating its biological activity

Journal of Chromatography Open
This study used LC/High resolution Orbitrap-mass spectrometry (LC/HR Orbitrap-MS) to comprehensively investigate the phenolic compound profile and biological activities of E. cardiophylla a species endemic to Türkiye. The leaf and root methanol extracts
Inan Dursun, Lütfi Behçet, Cemil Aydoğan   +2 more
doaj   +1 more source

Signature Ions in MS/MS Spectra for Dansyl-Aminohexyl-QQIV Adducts on Lysine

Molecules, 2020
Bacterial transglutaminase was used to label human plasma proteins with fluorescent tags. Protein lysines were modified with dansyl-epsilon-aminohexyl-Gln-Gln-Ile-Val-OH (dansylQQIV), while protein glutamines were modified with dansyl cadaverine. Labeled
Lawrence M. Schopfer, Oksana Lockridge
doaj   +1 more source

A description of the LC MS/MS parameters for the Orbitrap Exploris 480, which acquired the data for Fig 3 only.

, 2023
A description of the LC MS/MS parameters for the Orbitrap Exploris 480, which acquired the data for Fig 3 only.
Jordan B. Burton (17125170), Christina D. King (8879360), Joanna Bons (9458931), Amy O’Broin (17125173), Birgit Schilling (31153), Tamara Alliston (265049), Sandip K. Patel (13041543), Jacob P. Rose (17125167), Charles A. Schurman (4386745)   +8 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Maximizing MS/MS Acquisition for Lipidomics Using Capillary Separation and Orbitrap Tribrid Mass Spectrometer

, 2022
Liquid chromatography-mass spectrometry (LC-MS) is a typical strategy for lipidomics analysis. Although capillary LC-MS is a common analytical technique for proteomics analysis, its application to lipidomics has been limited.
Katherine A. Overmyer (10178250), Yuchen He (5057375), Paul D. Hutchins, Dain R. Brademan (5532608), Yuchen He, Joshua J. Coon, Dain R. Brademan, Paul D. Hutchins (7042742), Joshua J. Coon (388014), Katherine A. Overmyer   +9 more
core   +2 more sources

LC-ESI-LTQ-Orbitrap-MS for Profiling the Distribution of Oleacein and Its Metabolites in Rat Tissues

Antioxidants, 2021
The purpose of this work was to study the distribution of oleacein (OLEA) and its metabolites in rat plasma and different tissues, namely brain, heart, kidney, liver, lung, small intestine, spleen, stomach, skin, and thyroid, following the acute intake ...
Anallely López-Yerena, A. Vallverdú-Queralt, R. Lamuela-Raventós, Elvira Escribano-Ferrer   +3 more
semanticscholar   +1 more source