Results 261 to 270 of about 125,401 (357)

circPDE4B downregulation triggers GEMIN5‑dependent translational stress response and autophagy to reduce MAPT pathology

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Circular RNAs (circRNAs) are emerging as key regulators of gene expression, synaptic plasticity, and neuronal function in Alzheimer's disease (AD). Here, we characterize the biological actions of circPDE4B, a highly expressed circRNA markedly reduced in AD. METHODS circPDE4B knockdown in neuronal progenitor cells was combined with
Sambhavi Puri, Sophie J. F. van der Spek, Mintao Lin, Zihan Wang, Jacob Porter, Junming Hu, Liyuan Hu, Alejandro N. Rondón‐Ortiz, Alexander Knyshov, Jenna L. Libera, Scott E. Counts, Debomoy K. Lahiri, Julia TCW, Andrew Emili, Xiaoling Zhang, Benjamin Wolozin   +15 more
wiley   +1 more source

Rheological and mechanical performance of sustainable LC3 concrete modified with nano-silica and rubber latex. [PDF]

Sci Rep
Rath B, Praveenkumar TR, Gupta KK, Paramasivam P, Jayanthiladevi A, Tufa MA.   +5 more
europepmc   +1 more source

VGLL3 Regulates DAPK2‐Mediated Autophagy During Osteoblast Differentiation

BioFactors, Volume 52, Issue 3, May/June 2026.
VGLL3 regulates autophagic activity during osteoblast differentiation and is associated with DAPK2‐mediated autophagy. Overexpression of Dapk2 partially restores autophagy and osteogenic differentiation in Vgll3‐deficient osteoblasts. ABSTRACT Vestigial‐like family member 3 (VGLL3), a transcriptional cofactor of the TEA domain family, has been ...
Yuhan He, Ziyi Wang, Yao Weng, Heriati Sitosari, Yilin Zheng, Yaxin Qu, Mika Ikegame, Hirohiko Okamura   +7 more
wiley   +1 more source

The Roles of Alix and VPS4A in Autophagy and Endosomal Pathways and Their Relation to HBV Replication. [PDF]

FASEB J
Li J, Kemper T, Tong S, Wang X, Lin Y, Lu M.   +5 more
europepmc   +1 more source

Stanniocalcin 2‐Induced Autophagy Confers Resistance of Lung Cancer Cells to EGFR Inhibition via the ERK/Beclin 1 Signaling

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Although epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) are effective in treating NSCLC with EGFR mutations, the development of resistance limits their long‐term efficacy. Autophagy has been implicated as a potential mechanism behind this acquired resistance.
Yi‐Nan Liu, Yi‐Ling Chen, Meng‐Feng Tsai, Shang‐Gin Wu, Tzu‐Hua Chang, Tzu‐Hsiu Tsai, Jin‐Yuan Shih   +6 more
wiley   +1 more source

The autophagy switch: A critical determinant of arsenic-induced carcinogenesis and cancer therapy. [PDF]

Toxicol Rep
Zeinvand-Lorestani M, Rahim F, Zeinvand-Lorestani H.   +2 more
europepmc   +1 more source

Design, Synthesis, Biological Evaluation, and Molecular Modeling Studies of Novel 2‐Aminothiazole Derivatives as Potential FOXM1 Inhibitors for Triple‐Negative Breast Cancer Therapy and Structure‐Activity Relationship

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Triple Negative Breast Cancer (TNBC) is one of the most aggressive subtypes of breast cancer (BC), which is associated with a very poor prognosis. It is a broad category of tumors with a variety of biological, clinical, and morphological characteristics.
Khaled A. N. Abusharkh, Venhar Çınar, Alper Onder, Merve Sıkık, Mustafa Guzel, Zuhal Hamurcu, Bulent Ozpolat, Mehmet Ay, Ferah Comert Onder   +8 more
wiley   +1 more source

Circ-RERE promotes autophagy and immune escape in acute myeloid leukemia involving the miR-128-3p/ZEB1/PD-L1 axis. [PDF]

Clinics (Sao Paulo)
Shi X, Wang T, Sha K, Li S, Pei R, Lu Y.
europepmc   +1 more source

Evolution of Resistance to Avian Malaria Infection in an Endemic Hawaiian Honeycreeper

Ecology and Evolution, Volume 16, Issue 5, May 2026.
Hawaiian honeycreepers, a group of endemic song birds, represent one of the most stunning examples of an adaptive radiation. An evolutionary history devoid of malaria‐causing parasites has made them incredibly susceptible to disease. This work sought to identify genomic correlates of avian malaria infection.
John H. Neddermeyer, Loren Cassin‐Sackett, Eben H. Paxton, Michael G. Campana, Robert C. Fleischer, Jeffrey T. Foster   +5 more
wiley   +1 more source