Results 281 to 290 of about 125,401 (357)

Role of COL1A1 and CD44 in Modulating JAK1/STAT3‐Mediated Autophagy for Spinal Cord Injury Recovery

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.
ABSTRACT Spinal cord injury (SCI) is a severe trauma to the central nervous system that often leads to motor and sensory dysfunction in patients, severely affecting their quality of life. Autophagy plays a role in the pathological process of SCI, but the specific mechanism of autophagy in this case is unknown.
Chun‐Lei Li   +3 more
wiley   +1 more source

HIV-1 Vpr is targeted for degradation by autophagy. [PDF]

open access: yesPLoS Pathog
Chen Y   +4 more
europepmc   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao   +7 more
wiley   +1 more source

MAVISp: A modular structure‐based framework for protein variant effects

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract The role of genomic variants in disease has expanded significantly with the advent of advanced sequencing techniques. The rapid increase in identified genomic variants has led to many variants being classified as Variants of Uncertain Significance or as having conflicting evidence, posing challenges for their interpretation and ...
Matteo Arnaudi   +32 more
wiley   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska   +6 more
wiley   +1 more source

SensHB.Q: A Cost‐Effective Force‐Sensitive Handlebar to Control Omnidirectional Robots and Wheelchairs

open access: yesJournal of Field Robotics, Volume 43, Issue 3, Page 1471-1483, May 2026.
ABSTRACT This paper details the design and development of SensHB.Q, a force‐sensitive handlebar intended for caregivers driving electric‐powered wheelchairs, particularly those with omnidirectional mobility. The same interface can also be used in the future to operate other omnidirectional motorized systems, such as mobile robots, hospital beds, and ...
Luigi Tagliavini, Giuseppe Quaglia
wiley   +1 more source

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