Role of COL1A1 and CD44 in Modulating JAK1/STAT3‐Mediated Autophagy for Spinal Cord Injury Recovery
ABSTRACT Spinal cord injury (SCI) is a severe trauma to the central nervous system that often leads to motor and sensory dysfunction in patients, severely affecting their quality of life. Autophagy plays a role in the pathological process of SCI, but the specific mechanism of autophagy in this case is unknown.
Chun‐Lei Li +3 more
wiley +1 more source
HIV-1 Vpr is targeted for degradation by autophagy. [PDF]
Chen Y +4 more
europepmc +1 more source
RNA Modifications: Current Understandings and Future Perspectives
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Multi-Dimensional Assessment of Low-Carbon Engineering Cement-Based Composites Based on Rheological, Mechanical and Sustainability Factors. [PDF]
Jiang Z +5 more
europepmc +1 more source
MAVISp: A modular structure‐based framework for protein variant effects
Abstract The role of genomic variants in disease has expanded significantly with the advent of advanced sequencing techniques. The rapid increase in identified genomic variants has led to many variants being classified as Variants of Uncertain Significance or as having conflicting evidence, posing challenges for their interpretation and ...
Matteo Arnaudi +32 more
wiley +1 more source
Prenatal lipopolysaccharide exposure programs cardiac fibrosis via dysregulating of connexin 43 in offspring rats. [PDF]
Wen Y, Yuan Y, Zhang H, Liu Y.
europepmc +1 more source
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska +6 more
wiley +1 more source
K48 and K63 linkage-competed ubiquitination of BECN1 promotes circPDE4D-mediated autophagy in chronic obstructive pulmonary disease. [PDF]
Chen TT +7 more
europepmc +1 more source
ABSTRACT This paper details the design and development of SensHB.Q, a force‐sensitive handlebar intended for caregivers driving electric‐powered wheelchairs, particularly those with omnidirectional mobility. The same interface can also be used in the future to operate other omnidirectional motorized systems, such as mobile robots, hospital beds, and ...
Luigi Tagliavini, Giuseppe Quaglia
wiley +1 more source
Docosahexaenoic Acid Modulates Autophagy and Confers Neuronal Resilience under Hypoxia-Reoxygenation Stress. [PDF]
Zamora F +5 more
europepmc +1 more source

