Results 1 to 10 of about 156,312 (100)

Linker Length Drives Heterogeneity of Multivalent Complexes of Hub Protein LC8 and Transcription Factor ASCIZ

open access: yesBiomolecules, 2023
LC8, a ubiquitous and highly conserved hub protein, binds over 100 proteins involved in numerous cellular functions, including cell death, signaling, tumor suppression, and viral infection. LC8 binds intrinsically disordered proteins (IDPs), and although
Douglas R. Walker   +8 more
semanticscholar   +1 more source

Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis

open access: yesDevelopment, 2023
Actin-related proteins (Arps) are classified according to their similarity to actin and are involved in diverse cellular processes. ACTL7B is a testis-specific Arp, and is highly conserved in rodents and primates.
G. Merges   +8 more
semanticscholar   +1 more source

Entering new circles: Expansion of the LC8/DYNLL1 interactome in the ciliary-centrosomal network through system-driven motif evolution

open access: yesbioRxiv, 2023
LC8 is a eukaryotic hub protein that presents a highly conserved interface recognized by short linear motifs (SLiMs) in partner proteins. LC8 was originally associated with the dynein motor complex and was also suggested to promote dimerization of ...
Mátyás Pajkos   +3 more
semanticscholar   +1 more source

Quantifying cooperative multisite binding in the hub protein LC8 through Bayesian inference

open access: yesbioRxiv, 2022
Multistep protein-protein interactions underlie most biological processes, but their characterization through methods such as isothermal titration calorimetry (ITC) is largely confined to simple models that provide little information on the intermediate,
Aidan B. Estelle   +3 more
semanticscholar   +1 more source

The interaction between LC8 and LCA5 reveals a novel oligomerization function of LC8 in the ciliary-centrosome system

open access: yesScientific Reports, 2022
Dynein light chain LC8 is a small dimeric hub protein that recognizes its partners through short linear motifs and is commonly assumed to drive their dimerization. It has more than 100 known binding partners involved in a wide range of cellular processes.
Tamás Szaniszló   +7 more
semanticscholar   +1 more source

Actl7b-deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis

open access: yesbioRxiv, 2022
Actin-related proteins (Arp) are classified according to their similarity to actin and are involved in diverse cellular processes. ACTL7B is a testis-specific Arp and highly conserved in rodents and primates. ACTL7B is specifically expressed in round and
G. Merges   +6 more
semanticscholar   +1 more source

Calendar systems and communication of deaf-blind children [PDF]

open access: yesSpecijalna Edukacija i Rehabilitacija, 2012
The aim of this paper is to explain the calendar systems and their role in teaching deaf-blind children. Deaf-blind persons belong to a group of multiple disabled persons. This disability should not be observed as a simple composite of visual and hearing
Jablan Branka, Stanimirov Ksenija
doaj   +1 more source

Addiction disorders, psychopathy and crime in the light of empirical studies results [PDF]

open access: yesSpecijalna Edukacija i Rehabilitacija, 2013
The paper is based on the available empirical researches and examines the scientific basis of widely accepted thesis about the connection of substance addiction, psychopathy and crime.
Radulović Danka
doaj   +1 more source

#6691 COMPREHENSIVE TWO-DAY IN-HOSPITAL ASSESSMENT MODE IS ASSOCIATED WITH THREE-YEAR AND FIVE-YEAR MORTALITY IN PERITONEAL DIALYSIS PATIENTS

open access: yesNephrology, Dialysis and Transplantation, 2023
The study aims to explore the relationship between a "comprehensive 2-day in-hospital assessment management mode” (C2IAMM) and survival and technical survival rates of patients undergoing peritoneal dialysis (PD). Eight hundred and thirty PD
Dengyan Ma   +7 more
semanticscholar   +1 more source

Propuestas educomunicativas desde Uniradio. De infantil a la Universidad

open access: yesEdmetic: Revista de Educación Mediática y TIC, 2016
La radio, como medio de comunicación social presenta un gran potencial como espacio abierto a la participación de todo el mundo –mayores y pequeños-. El eje vertebrador de este estudio ha sido describir una serie de buenas prácticas que hemos llevado a ...
Paloma Contreras Pulido   +2 more
doaj   +1 more source

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