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LC8, a ubiquitous and highly conserved hub protein, binds over 100 proteins involved in numerous cellular functions, including cell death, signaling, tumor suppression, and viral infection. LC8 binds intrinsically disordered proteins (IDPs), and although
Douglas R. Walker+8 more
semanticscholar +1 more source
Actin-related proteins (Arps) are classified according to their similarity to actin and are involved in diverse cellular processes. ACTL7B is a testis-specific Arp, and is highly conserved in rodents and primates.
G. Merges+8 more
semanticscholar +1 more source
LC8 is a eukaryotic hub protein that presents a highly conserved interface recognized by short linear motifs (SLiMs) in partner proteins. LC8 was originally associated with the dynein motor complex and was also suggested to promote dimerization of ...
Mátyás Pajkos+3 more
semanticscholar +1 more source
Quantifying cooperative multisite binding in the hub protein LC8 through Bayesian inference
Multistep protein-protein interactions underlie most biological processes, but their characterization through methods such as isothermal titration calorimetry (ITC) is largely confined to simple models that provide little information on the intermediate,
Aidan B. Estelle+3 more
semanticscholar +1 more source
Dynein light chain LC8 is a small dimeric hub protein that recognizes its partners through short linear motifs and is commonly assumed to drive their dimerization. It has more than 100 known binding partners involved in a wide range of cellular processes.
Tamás Szaniszló+7 more
semanticscholar +1 more source
Actin-related proteins (Arp) are classified according to their similarity to actin and are involved in diverse cellular processes. ACTL7B is a testis-specific Arp and highly conserved in rodents and primates. ACTL7B is specifically expressed in round and
G. Merges+6 more
semanticscholar +1 more source
Calendar systems and communication of deaf-blind children [PDF]
The aim of this paper is to explain the calendar systems and their role in teaching deaf-blind children. Deaf-blind persons belong to a group of multiple disabled persons. This disability should not be observed as a simple composite of visual and hearing
Jablan Branka, Stanimirov Ksenija
doaj +1 more source
Addiction disorders, psychopathy and crime in the light of empirical studies results [PDF]
The paper is based on the available empirical researches and examines the scientific basis of widely accepted thesis about the connection of substance addiction, psychopathy and crime.
Radulović Danka
doaj +1 more source
The study aims to explore the relationship between a "comprehensive 2-day in-hospital assessment management mode” (C2IAMM) and survival and technical survival rates of patients undergoing peritoneal dialysis (PD). Eight hundred and thirty PD
Dengyan Ma+7 more
semanticscholar +1 more source
Propuestas educomunicativas desde Uniradio. De infantil a la Universidad
La radio, como medio de comunicación social presenta un gran potencial como espacio abierto a la participación de todo el mundo –mayores y pequeños-. El eje vertebrador de este estudio ha sido describir una serie de buenas prácticas que hemos llevado a ...
Paloma Contreras Pulido+2 more
doaj +1 more source