Mediating role of SII in the association between LC9 and overactive bladder [PDF]
Scientific ReportsExtensive research suggests a potential association between the overactive bladder (OAB), Life’s Crucial 9 (LC9), and the systemic immune-inflammation index (SII).
Hongyang Gong
exaly +5 more sources
Examining the mediating function of SIRI in the association between LC9 and chronic obstructive pulmonary disease [PDF]
Frontiers in MedicineBackgroundChronic obstructive pulmonary disease (COPD) is a major contributor to early mortality, high overall mortality rates, and significant healthcare costs. Based on the Life’s Essential 8 (LE8), Life’s Crucial 9 (LC9) is a new cardiovascular health
Ziming Wang, Xinyun Xie, Hongyang Gong
exaly +6 more sources
The association between Life's Crucial 9 (LC9) and low muscle mass (LMM): The mediating role of Dietary Inflammatory Index (DII). [PDF]
Medicine (United States)Some studies suggest a potential link between cardiovascular health, inflammation, and low muscle mass (LMM). However, the mechanisms through which inflammation influences the relationship between cardiovascular health and LMM remain unclear.
Hongyang Gong, Shaoqun Huang
exaly +3 more sources
Life’s Crucial 9 score and chronic kidney disease: insights from NHANES 2005–2018 and the mediating role of systemic inflammation and oxidative stress [PDF]
Frontiers in MedicineBackgroundChronic kidney disease (CKD) is a growing global health burden, closely linked to metabolic and cardiovascular risk factors. Life’s Crucial 9 (LC9) is a novel health assessment tool that expands upon Life’s Essential 8 (LE8) by incorporating ...
Qiuyang Li, Zhengyun Ren
exaly +4 more sources
Central adiposity indices and inflammatory markers mediate the association between life’s crucial 9 and periodontitis in US adults [PDF]
Lipids in Health and DiseaseBackground Periodontitis, a chronic inflammatory disease, is closely linked to cardiovascular health. While Life’s Essential 8 (LE8) evaluates cardiovascular metrics, recent recommendations suggest incorporating psychological health (PHQ-9) to form Life ...
Jia-Jie Guo +10 more
exaly +3 more sources
Genome Sequences of New Faustovirus Strains ST1 and LC9, Isolated from the South of France. [PDF]
Genome Announcements, 2017 ABSTRACT Faustoviruses are amoeba-infecting giant viruses closely related to the Asfarviridae family. Here, we report the isolation, genome sequencing, and annotation of ST1 and LC9, two new strains belonging to lineages L and E9 of faustoviruses, currently represented by only one representative each.
Bernard La Scola +2 more
exaly +3 more sources
Crystal structure of metagenome-derived LC9-RNase H1 with atypical DEDN active site motif [PDF]
FEBS Letters, 2013 The crystal structure of metagenome‐derived LC9‐RNase H1 was determined. The structure‐based mutational analyses indicated that the active site motif of LC9‐RNase H1 is altered from DEDD to DEDN. In this motif, the location of the second glutamate residue is moved from αA‐helix to β1‐strand immediately next to the first aspartate residue, as in the ...
Yuichi Koga +2 more
exaly +3 more sources
Life’s crucial 9, plasma proteomics, and the risk of major complications and mortality in MASLD [PDF]
npj Metabolic Health and DiseaseMetabolically dysfunction-associated steatotic liver disease (MASLD) constitutes a major health burden. Whether a multidomain profile of modifiable health, as captured by Life’s Crucial 9 (LC9), is associated with major complications in MASLD, and which ...
Bing-Yun Zhang +15 more
doaj +2 more sources
Association between Life’s Crucial 9 and psoriatic arthritis in U.S. adults: a cross-sectional study [PDF]
Frontiers in MedicineBackgroundPsoriatic arthritis (PsA) has been closely associated with an elevated risk of cardiovascular disease (CVD). Nevertheless, the connection between Life’s Crucial 9 (LC9), which serves as a holistic measure of cardiovascular health (CVH), and PsA
Jiefeng Jiang +11 more
doaj +2 more sources
Comparing the predictive accuracy of life’s essential 8 and life’s crucial 9 scores for all-cause mortality in COPD patients among US adults: a prospective cohort study [PDF]
BMC Public HealthBackground Life’s Essential 8 (LE8) represents an established score for quantifying cardiovascular health (CVH). Life’s Crucial 9 (LC9) is a newly proposed metric that integrates psychological health with LE8.
Shuhui Qiu +5 more
doaj +2 more sources