Results 91 to 100 of about 4,532 (131)

Lymphocytic Choriomeningitis Virus (LCMV) and Pregnancy: Facts and Prevention [PDF]

open access: yes
Lymphocytic choriomeningitis virus (LCMV) is carried by wild mice. Laboratory rodents and pet rodents, such as hamsters and guinea pigs, can become infected with LCMV from contact with wild mice.

core   +2 more sources

Immunological tolerance to LCMV antigens differently affects control of acute and chronic virus infection in mice

open access: yes, 2017
Cytotoxic T lymphocytes (CTLs) play a key role in the control of lymphocytic horiomeningitis virus (LCMV) infection. In C57BL/6 mice (H‐2b), the CTL response is mainly directed against epitopes from the LCMV glycoprotein (GP) and the nucleoprotein (NP ...
Woopen, Christina   +21 more
core   +1 more source

Spatial and Temporal Dynamics of Lymphocytic Choriomeningitis Virus in Wild Rodents, Northern Italy

open access: yesEmerging Infectious Diseases, 2009
We determined the prevalence of infection with lymphocytic choriomeningitis virus (LCMV) among small mammals in northern Italy and analyzed long-term dynamics of LCMV in a rodent population in the province of Trento.
Valentina Tagliapietra   +8 more
doaj   +1 more source

Normal in vivo anti-LCMV immune responses of STRA6 KO mice.

open access: yes, 2013
A. Spleen cell numbers on day 8 after LCMV infection. Means ± SD of absolute numbers of total splenocytes, CD4+ cells, and CD8+ cells in spleens of WT littermate control (n = 4) and KO (n = 4) mice on day 8 post-LCMV infection are presented.
Xuehai Wang (305003)   +10 more
core   +1 more source

Modulation of SIV and HIV DNA Vaccine Immunity by Fas-FasL Signaling

open access: yesViruses, 2015
Signaling through the Fas/Apo-1/CD95 death receptor is known to affect virus-specific cell-mediated immune (CMI) responses. We tested whether modulating the Fas-apoptotic pathway can enhance immune responses to DNA vaccination or lymphocytic ...
Jiabin Yan   +3 more
doaj   +1 more source

Accelerated and improved quantification of lymphocytic choriomeningitis virus (LCMV) titers by flow cytometry. [PDF]

open access: yes, 2012
Lymphocytic choriomeningitis virus (LCMV), a natural murine pathogen, is a member of the Arenavirus family, may cause atypical meningitis in humans, and has been utilized extensively as a model pathogen for the study of virus-induced disease and immune ...
Darlynn Korns Johnson   +3 more
core   +1 more source

Development and optimization of the LCMV-NP FACS assay.

open access: yes, 2012
A 3-fold dilution series of a 1×106 PFU/ml LCMV Arm virus stock was produced, incubated with Vero cells, and intracellular LCMV-NP levels were detected by FACS as described in Methods.
Dirk Homann (164006)   +1 more
core   +1 more source

Novel mechanism of arenavirus-induced liver pathology.

open access: yesPLoS ONE, 2015
Viral hemorrhagic fevers (VHFs) encompass a group of diseases with cardinal symptoms of fever, hemorrhage, and shock. The liver is a critical mediator of VHF disease pathogenesis and high levels of ALT/AST transaminases in plasma correlate with poor ...
Juliane I Beier   +7 more
doaj   +1 more source

Further optimization of the LCMV-NP FACS assay.

open access: yes, 2012
(A) The minimum virus exposure time required to detect LCMV-NP was ascertained by incubating 3-fold serial dilutions of a 1×106 PFU/ml LCMV Arm stock with Vero cells for 2, 4, 6, 8, and 24 hours and subsequent determination of LCMV-NP expression by FACS ...
Dirk Homann (164006)   +1 more
core   +1 more source

Emerg Infect Dis

open access: yes
During follow-up of a 2012 US outbreak of lymphocytic choriomeningitis virus (LCMV), we conducted a trace-forward investigation. LCMV-infected feeder mice originating from a US rodent breeding facility had been distributed to >500 locations in 21 states.

core  

Home - About - Disclaimer - Privacy