Results 81 to 90 of about 6,085 (188)

Combined lung atypical carcinoid, LCNEC and ADC

, 2013
Although the 2004 World Health Organization classification attempted to clarify the role of combined neuroendocrine tumors of the lung, these are yet to be clearly defined. Problems concerning clinical behavior are a result of unclear pathophysiology, the limited number of published cases, and the heterogeneity of histotypes involved.
Michele Giansanti, Renato Colella, Francesco Puma, Niccolò Daddi, Mark Ragusa, Damiano Vinci   +5 more
openaire   +1 more source

Pathological features, clinical presentations and prognostic factors of ovarian large cell neuroendocrine carcinoma: a case report and review of published literature

Journal of Ovarian Research, 2019
Background There is no consensus on the optimal chemotherapy regimen and the prognostic factors for ovarian large cell neuroendocrine carcinoma (LCNEC), a rare type of tumor. The objective of the present study is to present the case of a recent encounter
Xiaohang Yang, Junyu Chen, Ruiying Dong
doaj   +1 more source

A case of combined large cell neuroendocrine carcinoma (LCNEC) and squamous cell carcinoma.

The Journal of the Japanese Association for Chest Surgery, 2002
症例は52歳男性.2000年1月, 胸部X線写真上, 右上肺野に急速に増大した腫瘤影を認め当院に紹介された.胸部CT上, 右上葉に11×10×9.0cm大の腫瘤を認め, 縦隔リンパ節の腫大は認めなかった.腫瘍マーカーはSLX, SCC, CYFRA, NSEが上昇していた.原発性肺癌を強く疑い, 同年1月25日に右上葉切除・ND2a・胸壁 (第3肋骨) 合併切除術を施行した.病理組織学的に扁平上皮癌の成分とLarge cell neuroendocrine carcinoma (LCNEC) の成分を混在しており, 扁平上皮癌を混在したLCNECと診断され, 術後病期はpT3N0M0, Stage II Bであった.術後経過は良好であり, 化学療法を施行せずに退院した.以後 ...
Sugimoto, Seiichiro, Mizutani, Hisao, Kayano, Koichi, Teramoto, Shigeru   +3 more
openaire   +2 more sources

Table3_Whole-genome characterization of large-cell lung carcinoma: A comparative analysis based on the histological classification.DOCX

, 2023
Background: According to the 2015 World Health Organization classification, large cell neuroendocrine carcinoma (LCNEC) was isolated from Large-cell lung cancer (LCLC) tumors, which constitutes 2%–3% of non-small cell lung cancer (NSCLC).
Xiaowei Wu (2031751), Jin Yin (219996), Yukun Zu (14323782), Yu Deng (162738)   +3 more
core   +1 more source

Large-cell neuroendocrine carcinoma (LCNEC) without pulmonary symptoms diagnosed in a cutaneous metastasis.

The American journal of case reports, 2014
Female, 60 FINAL DIAGNOSIS: Large-cell neuroendocrine carcinoma Symptoms: Back pain Medication: - Clinical Procedure: Vertebroplasty Specialty: Oncology.Unusual clinical course.An atypical presentation of large-cell neuroendocrine carcinoma was diagnosed from a metastatic nodule on the chest wall.The patient was a 60-year-old female who presented with ...
Yuan, Cai, Keating, Benjamin, Farricielli, Laurie A., Zhang, Kuixing   +3 more
openaire   +2 more sources

Comprehensive Analysis of Neurogenic Differentiation Factor 1 (NEUROD1), Achaete-Scute Homolog 1 (ASCL1), POU Class 2 Homeobox 3 (POU2F3), and Yes-Associated Protein 1 (YAP1) Expression Signatures Reveals Unique Large-Cell Neuroendocrine Carcinoma (LCNEC) Subgroups With Potential Therapeutic Implications

Large-cell neuroendocrine carcinoma (LCNEC) can be genomically subtyped into small-cell lung cancer (SCLC) and non-SCLC–like. Neurogenic differentiation 1 (NEUROD1), achaete-scute homolog 1 (ASCL1), POU class 2 homeobox 3 (POU2F3), and yes-associated ...
Hillen, Lisa M, Rijnsburger, Nicole, Dingemans, Anne-Marie C, von der Thüsen, Jan H, Heijboer, Frank W J, Derks, Jules L, Mustafa, Dana A M, Speel, Ernst-Jan M, Hermans, Bregtje C M   +8 more
core   +1 more source

Spontaneous regression of recurrent pulmonary large cell neuroendocrine carcinoma with alteration of PD‐L1 expression after surgical resection: A case report

Thoracic Cancer
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive subtype of non‐small cell lung cancer with a poor prognosis. Spontaneous regression, that is, partial or complete disappearance of a malignancy without medical intervention ...
Green Hong, Chaeuk Chung, Dongil Park, Song‐I Lee, Jeong Eun Lee, Da Hyun Kang   +5 more
doaj   +1 more source

A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder

Case Reports in Medicine, 2013
Large cell neuroendocrine carcinoma (LCNEC) of the urinary bladder is very rare. Definite treatment strategy has not been established and prognosis of the disease is not clear yet.
Shinro Hata, Yoshihisa Tasaki
doaj   +1 more source

LCNEC of Nasal Cavity: Diagnostic and Treatment Modalities—Case Report and a Narrative Review

Indian Journal of Medical and Paediatric Oncology
Abstract Large cell neuroendocrine carcinoma (LCNEC) of the nasal cavity is a rare epithelial malignancy with only a few cases reported to date. In this article, we present a case report of a 48-year-old male, who presented with a history of epistaxis and nasal blockage for over 1 year and was initially diagnosed as undifferentiated ...
Gaurav Jalal, T.V.S.V.G.K. Tilak
openaire   +1 more source

Treatment status, survival and gene expression analysis of large-cell neuroendocrine lung carcinoma: a real-world study in China

Therapeutic Advances in Medical Oncology
Background: Large-cell neuroendocrine lung carcinoma (LCNEC) is a rare subtype of lung cancer that lacks standard treatment at present. Purpose: This study aimed to investigate the treatment status, failure pattern, survival outcome, and gene expression ...
Fei Qi, Minghang Zhang, Yi Han, Juan Du, Hongjie Yang, Hongmei Zhang, Yong Zhang, Tongmei Zhang   +7 more
doaj   +1 more source