Results 31 to 40 of about 20,068,597 (246)

Immunotoxin LD₅₀ determined on model C-MYC and control 1B4F4 cells.

, 2013
*More than this value**LD50(1B4F4)/LD50(C-MYC)
Alexander G. Tonevitsky (350317), Oleg A. Stremovskiy (301803), Dmitry S. Balabashin (350315), Alexey V. Stepanov (350306), Alexey A. Belogurov Jr. (350307), Alexander G. Gabibov (350318), Ivan V. Smirnov (350313), Sergey M. Deyev (301805), Leonid V. Kozlov (350310), Lidia P. Sashchenko (350316), Alain Friboulet (341694), Sergey E. Dmitriev (350312), Natalia A. Ponomarenko (350308), Anna M. Bichucher (350311), Olga G. Shamborant (350314)   +14 more
core   +1 more source

Identification of the primary sensitizing mite (dominant mite) in patients with allergic respiratory disease sensitized to Dermatophagoides pteronyssinus and Lepidoglyphus destructor

World Allergy Organization Journal
Objective: To identify the dominant mite in patients with allergic respiratory disease (ARD) and double sensitization to Dermatophagoides pteronyssinus (Dpt) and Lepidoglyphus destructor (Ld).
José Arias-Irigoyen, MD, Irene Arias-Talavera, MD, Manuel Lombardero, PhD, Agustín Galán, BSc, Rafael I. Monsalve, PhD   +4 more
doaj   +1 more source

Effects of intravenous lidocaine, dexmedetomidine, and their combination on IL-1, IL-6 and TNF-α in patients undergoing laparoscopic hysterectomy: a prospective, randomized controlled trial

BMC Anesthesiology, 2021
Background Surgical-related inflammatory responses have negative effects on postoperative recovery. Intravenous (IV) lidocaine and dexmedetomidine inhibits the inflammatory response.
Siqi Xu, Shenghong Hu, Xia Ju, Yuanhai Li, Qing Li, Shengbin Wang   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Intracellular localization of LdFlabarin.

, 2013
L. amazonensis BA125 cells were co-transfected with pNUS mRednD-LdFlabarin and pNUS LdFlabarin-GFPcH. (A–B) Fluorescence images from a cell expressing both mRed-LdFlabarin (red)(A) and LdFlabarin-GFP (green) (B). (C) Overlay of A and B.
Emmanuel Tetaud (40495), Bénédicte Salin (48466), Benoît Espiau (40494), Magali Thonnus (183905), Christelle Metzler (463787), Fanny Boissier (463785), Corinne Blancard (463786), Michèle Lefebvre (463784), Cécile Sauvanet (118310), Annelise Sahin (40493), Gilles Merlin (40499)   +10 more
core   +1 more source

Error performance analysis of generalized quadrature spatial modulation with labelling diversity

Scientific Reports
Multiple-input multiple-output (MIMO) generalised spatial modulation (GSM) systems represent a pivotal advancement in wireless communication technology. These systems have unlocked the potential for enhanced data rates and enhanced error performance (EP).
Nathael Sibanda, Hongjun Xu, Narushan Pillay   +2 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Toxicity and Lethal Effect of Greenhouse Insecticides on Coccinella septempunctata (Coleoptera: Coccinellidae) as Biological Control Agent of Myzus persicae (Hemiptera: Aphididae)

Toxics, 2023
Deltamethrin and imidacloprid are commonly used insecticides for controlling sub-sucking insects in greenhouses. However, their application may cause sublethal effects on the aphid coccinellid predator Coccinella septempunctata (Coleoptera: Coccinellidae)
Panagiotis J. Skouras, Eirini Karanastasi, Ioannis Lycoskoufis, Vasilis Demopoulos, Anastasios I. Darras, Athanasios Tsafouros, Polina C. Tsalgatidou, John T. Margaritopoulos, George J. Stathas   +8 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source