Results 41 to 50 of about 246,841 (288)

A High Cattle-Grazing Density Alters Circadian Rhythmicity of Temperature, Heart Rate, and Activity as Measured by Implantable Bio-Loggers

Frontiers in Physiology, 2021
Six cows managed under extensive grazing conditions were used to study the effect of moving the animals to a higher grazing density on the circadian rhythms of temperature (T), heart rate (HR), and activity (ACT), which were recorded by implantable bio ...
Carlos Palacios, Javier Plaza, José-Alfonso Abecia   +2 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Electron-based crystalline undulator

, 2007
We discuss the features of a crystalline undulator of the novel type based on the effect of a planar channeling of ultra-relativistic electrons in a periodically bent crystals.
, Adejshvili D I, Adejshvili D I, Adejshvili D I, Alferov D F, Andrei V Korol, Andrey V Solov'yov, Baier V N, Baier V N, Baranov V T, Baranov V T, Biruykov V M, Carrigan R A, Hubbel J H Seltzer S M, Kaplin V V, Korol A V, Korol A V, Korol A V, Korol A V, Korol A V, Korol A V, Krause W, Kumakhov M A, Kumakhov M A, Lindhard J, Mehdi Tabrizi, Rullhusen P, Tabrizi M, Walter Greiner, Yao W M   +29 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Genetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility.

PLoS ONE, 2012
High dose ionizing radiation (IR) is a well-known risk factor for breast cancer but the health effects after low-dose (LD,
Antoine M Snijders, Francesco Marchetti, Sandhya Bhatnagar, Nadire Duru, Ju Han, Zhi Hu, Jian-Hua Mao, Joe W Gray, Andrew J Wyrobek   +8 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Genome-wide divergence and linkage disequilibrium analyses for Capsicum baccatum revealed by genome-anchored single nucleotide polymorphisms

Frontiers in Plant Science, 2016
Principal component analysis (PCA) with 36,621 polymorphic genome-anchored single nucleotide polymorphisms (SNPs) identified collectively for Capsicum annuum and Capsicum baccatum was used to show the distribution of these 2 important incompatible ...
Padma Nimmakayala, Venkata Lakshmi Abburi, Thangasamy Saminathan, Aldo Almeida, Brittany Davenport, Joshua Davidson, Chandra Mohan Reddy, Gerald Hankins, Andreas Ebert, Doil Choi, John Stommel, Umesh K Reddy   +11 more
doaj   +1 more source

TRAILER HEAT ZONES AND THEIR RELATION TO HEAT STRESS IN PIG TRANSPORT

Engenharia Agrícola, 2021
This study evaluates the dynamics of heat zones in the load and its relationship with the stress of pigs during transport. Four journeys of 170 km were monitored, recording the physiological variables of 192 animals (48 per journey), namely rectal ...
Nítalo A. F. Machado, José A. D. Barbosa-Filho, Geraldo L. B. Ramalho, Héliton Pandorfi, Iran J. O. Da Silva   +4 more
doaj   +1 more source

$L^2$ Analysis of the Multi-Configuration Time-Dependent Hartree-Fock Equations

, 2010
The multiconfiguration methods are widely used by quantum physicists and chemists for numerical approximation of the many electron Schr\"odinger equation.
Mauser, Norbert J., Trabelsi, Saber
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source