Results 61 to 70 of about 20,068,597 (246)

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

Regional LD plots for the four C-type MRE-SNPs overlapping with the GWAS Catalog.

, 2015
Regional LD plots for the four C-type MRE-SNPs overlapping with the GWAS Catalog.
Silva Kasela (817613), Urmo Võsa (102394), Tarmo Annilo (154551), Tõnu Esko (102379)   +3 more
core   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Exo-TiC/ExoTiC-LD: ExoTiC-LD v3.2.0

<p>ExoTiC-LD v3.2.0 is a major update to the ExoTiC-LD package that is fully back compatible with older versions.</p> <p>Local data is not longer required and the desired models are downloaded automatically for each run.
David Grant, Hannah Wakeford
core   +1 more source

Proteome-level assessment of origin, prevalence and function of Leucine-Aspartic Acid (LD) motifs.

, 2018
MOTIVATION:Leucine-aspartic acid (LD) motifs are short linear interaction motifs (SLiMs) that link paxillin family proteins to factors controlling cell adhesion, motility and survival.
Gao, Xin, Alam, Tanvir, Astro, Veronica, Canlas, Christian G, Momin, Afaque Ahmad Imtiyaz, Ali, Amal J., Adamo, Antonio, Alazmi, Meshari, Jaremko, Mariusz, Huser, Franceline, Naser, Rayan Mohammad Mahmoud, Huser, Raphaël, Jaremko, Lukasz, Merzaban, Jasmeen, Bajic, Vladimir B., Arold, Stefan T., Hong, Seungbeom, Walkiewicz, Katarzyna Wiktoria   +17 more
core   +1 more source

X-LDR: an atlas of linkage disequilibrium across species

Genome Biology
To reach a genomic scale illustration for linkage disequilibrium (LD), we introduce X-LDR, a stochastic algorithm for biobank-scale data ( $$\mathcal {O}(nmB)$$ , n the sample size, m the number of SNPs, and B iterations).
Tian-Neng Zhu, Xing Huang, Meng-Yuan Yang, Guo-An Qi, Qi-Xin Zhang, Feng Lin, Wenjing Zhang, Zhe Zhang, Xin Jin, Hou-Feng Zheng, Hai-Ming Xu, Shizhou Yu, Guo-Bo Chen   +12 more
doaj   +1 more source

Anti‐CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine, Fabien Rollot, Romain Casey, Nicolas Collongues, Sandra Vukusic, Guillaume Mathey, Anne Laure Dubessy, Jonathan Ciron, Jérôme De Seze, Aurélie Ruet, Pierre Labauge, Arnaud Kwiatkowski, Hélène Zephir, Caroline Papeix, Gilles Defer, Christine Lebrun‐Frenay, David Axel Laplaud, Eric Berger, Eric Thouvenot, Jean Pelletier, Abdullatif Al Khedr, Olivier Casez, Bertrand Bourre, Abir Wahab, Laurent Magy, Jean‐Philippe Camdessanché, Ines Doghri, Solène Moulin, Mariana Sarov Rivière, Karolina Hankiewicz, Amélie Dos Santos, Corinne Pottier, Eric Manchon, Jennifer Aboab, Maia Tchikviladze, Thomas David, Gilles Edan, Emmanuelle Le Page, Laure Michel, Anne Kerbrat, OFSEP Investigators   +40 more
wiley   +1 more source

LdFlabarin binds and tubulates liposomes in vitro.

, 2013
Electron micrographs of liposomes incubated with purified recombinant LdFlabarin-His6 (A–C, F) with LdFlabarin without His-tag (E) or with BSA (D).
Emmanuel Tetaud (40495), Bénédicte Salin (48466), Benoît Espiau (40494), Magali Thonnus (183905), Christelle Metzler (463787), Fanny Boissier (463785), Corinne Blancard (463786), Michèle Lefebvre (463784), Cécile Sauvanet (118310), Annelise Sahin (40493), Gilles Merlin (40499)   +10 more
core   +1 more source

Reaction to the LEXUS review in the LD&C, Vol.3, No 2

, 2010
This technology review gives an overview of LEXUS, the MPI online lexicon tool and its new functionalities. It is a reaction to a review of Kristina Kotcheva in Language Documentation and Conservation 3(2).
Ringersma, Jacquelijn, Kemps-Snijders, Marc   +1 more
openaire   +1 more source

Bibliometric and Visual Analysis of the Current Status and Trends of Postoperative Pain in Children from 1950–2021

Journal of Pain Research, 2022
Cong Wang,1 Li-Dan Liu,1 Xue Bai2 1Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Health Management, Shengjing Hospital of China Medical University, Shenyang, People’s ...
Wang C, Liu LD, Bai X
doaj