Results 71 to 80 of about 251,423 (287)

Experimental Demonstration of a Quantum Circuit using Linear Optics Gates

, 2004
One of the main advantages of an optical approach to quantum computing is the fact that optical fibers can be used to connect the logic and memory devices to form useful circuits, in analogy with the wires of a conventional computer.
B. C. Jacobs, J. D. Franson, M. A. Nielsen, T. B. Pittman   +3 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Comparative immune responses against Psoroptes ovis in two cattle breeds with different susceptibility to mange [PDF]

, 2015
The sheep scab mite, Psoroptes ovis, is a major problem in the beef cattle industry, especially in Belgian Blue (BB) cattle. This breed is naturally more predisposed to psoroptic mange but reasons for this high susceptibility remain unknown.
Chiers, Koen, Claerebout, Edwin, Geldhof, Peter, González Hernández, Ana, Grauwet, Korneel, Grit, Grietje, Sarre, Charlotte, Van Coppernolle, Stefanie, Van Den Broeck, Wim, Van Meulder, Frederik   +9 more
core   +4 more sources

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

X-LDR: an atlas of linkage disequilibrium across species

Genome Biology
To reach a genomic scale illustration for linkage disequilibrium (LD), we introduce X-LDR, a stochastic algorithm for biobank-scale data ( $$\mathcal {O}(nmB)$$ , n the sample size, m the number of SNPs, and B iterations).
Tian-Neng Zhu, Xing Huang, Meng-Yuan Yang, Guo-An Qi, Qi-Xin Zhang, Feng Lin, Wenjing Zhang, Zhe Zhang, Xin Jin, Hou-Feng Zheng, Hai-Ming Xu, Shizhou Yu, Guo-Bo Chen   +12 more
doaj   +1 more source

The LIL for $U$-statistics in Hilbert spaces

, 2007
We give necessary and sufficient conditions for the (bounded) law of the iterated logarithm for $U$-statistics in Hilbert spaces. As a tool we also develop moment and tail estimates for canonical Hilbert-space valued $U$-statistics of arbitrary order ...
C. Houdré, E. Giné, E. Giné, E. Giné, E. Giné, E.D. Gluskin, H. Rubin, M. Arcones, O. Bousquet, R. Adamczak, R. Latała, R. Latała, R. Latała, Radosław Adamczak, Rafał Latała, S. Kwapień, V. Goodman, V.H. la Peña de, V.H. la Peña de, V.H. la Peña de   +19 more
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Cross-diffusion driven instability in a predator-prey system with cross-diffusion

, 2014
In this work we investigate the process of pattern formation induced by nonlinear diffusion in a reaction-diffusion system with Lotka-Volterra predator-prey kinetics.
Lombardo, Maria Carmela, Sammartino, Marco, Tulumello, Eleonora   +2 more
core   +1 more source