Results 121 to 130 of about 57,088 (258)

LD50 of strain HA9801 on A/J mouse.

, 2012
LD50 of strain HA9801 on A/J mouse.
Hongjie Fan (167764), Wei Zhang (405), Jie Rong (181453), Chengping Lu (167772), Xiaohui Wang (19899), Huochun Yao (181458)   +5 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Penentuan LD50 Penyakit Infeksi Toxoplasma gondii pada Mencit balb/c [PDF]

, 2009
LD50 determination in toxoplasma gondii infection in balb/c mice Background: LD50 is a marker of virulence which is reflects degree of microorganism pathogenicity. LD50 of every pathogens to be used should be determined in order to choose an appropiate
Winarto, Winarto
core  

Comparison of uptake of four compounds (LD50) in zebrafish.

, 2015
Comparison of uptake of four compounds (LD50) in zebrafish.
Chang-Qin Hu (734332), Jing-Pu Zhang (346642), Wei Qin (205374), Fan Zhang (46132)   +3 more
core   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Determination of Suitable Dose of Gamma Ray for Mutation Induction in Pomegranate Buds (Punica Granatum L. cv. Malase Saveh) [PDF]

مجله علوم و فنون هسته‌ای, 2014
Pomegranate is cultivated in many regions of Iran. Due to the pomegranate sensitivity to the Carob moth, it is necessary to develop new cultivars that tolerate the Carob moth (Spectrobates ceratoniae). To induce a genetic variation in the plant, breeding
Sirous Vedadi, Behnam Naserian, Seyed Ziaodin Tabatabei, Masoud Rahimi   +3 more
doaj  

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, Volume 13, Issue 33, 15 June 2026.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1466-1475, June 2026.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

Uji Toksisitas Akut (LD50) Infusa Biji Borroco (Celosia Argenta L.) Pada Mencit Betina Secara Intraperitorial [PDF]

, 1997
Uji toksisitas akut infusa biji boroco ((Celosia Argenta L.) yang dipecah dan tanpa dipecah dilakukan melalui parameter LD50 untuk mengetahui berapa besar dosis yang dapat menyebabkan kematian separoh dari jumlah mencit betina dengan pemberian secara ...
Ariyani, Erna Sri
core  

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source