Results 131 to 140 of about 57,088 (258)

Gallic Acid‐Mediated Enhancement of Diazepam‐Induced Sedation via GABAA Receptor Modulation: In Vivo and In Silico Evaluation

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Gallic acid (GA) dose‐dependently reduced sleep latency and prolonged sleep duration in thiopental sodium‐induced mice, with synergistic effects when combined with diazepam. Molecular docking revealed GA's higher binding affinity (−9.8 kcal/mol) to GABAA receptor (α1 and β2 subunits) than diazepam (−8.4 kcal/mol), suggesting GABAergic potential ...
Noshin Tasnim Yana, Anike Chakrabarty, Chinmoy Kumar Saha, Nikhat Jamal Siddiqi, Norah Alnazhan, Md. Sakib Al Hasan, Feroz Khan Nun, Imam Hossen Rakib, Md. Nasimul Haque Shipon, Emon Mia, Md Asaduzzaman Jony, Ali Mohamod Wasaf Hasan, Muhammad Torequl Islam, Azmat Ali Khan   +13 more
wiley   +1 more source

Acute toxicity of ricazol administered as injection

Российский паразитологический журнал, 2016
Acute toxicity of Ricazol based on Ricobendazole by oral administration and intramuscular injection in white outbread mice and rats as well as by dermal ad-ministration in white rats is studied.
E. V. Abramova, I. A. Arkhipov
doaj  

Protective Role of Ziziphus lotus Fruits and Leaves Extracts Towards BPA‐Associated Testis Toxicity

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Aqueous extracts of Ziziphus lotus fruits and leaves show protective effects towards testis toxicity associated with oral bisphenol A exposure in a rat model, through the likely involvement of antioxidant activity. ABSTRACT Ziziphus lotus L. is used in folk medicine for various ailments.
Dhekra Grami, Soumaya Wahabi, Raja Jouini, Imen Hlel, Naoures Ochi, Slimen Selmi, Hichem Sebai, Luca De Toni   +7 more
wiley   +1 more source

Uji Toksisitas Akut (LD50) Infusa Daun Kembang Mentega (Nerium Oleander Linn) Pada Mencit Jantan Secara Intraperitonial [PDF]

, 1998
Uji toksisitas akut infusa daun kembang mentega dilakukan melalui parameter LD50 untuk mengetahui besarnya dosis yang dapat menyebabkan kematian separuh dari jumlah mencit jantan dengan pemberian secara intraperitonial.
Suwardhany, Neny
core  

Toxicological Evaluation of the Roots of Ficus pandurata Hance var. angustifolia Cheng

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Toxicological evaluation of the roots of Ficus pandurata Hance var. angustifolia Cheng for safe utilization. Two‐year‐old RFPH roots were prepared as an aqueous extract powder, with 1 g equivalent to 30 g of raw material. Acute oral toxicity, genotoxicity, teratogenicity, and 90‐day repeated‐dose oral toxicity tests were performed in SD rats and ICR ...
Yamin Chen, Zhijing Fu, Fangfang Ma, Siyuan Wang, Junjie Pan, Huaxing Luo, Zhen Liu, Jianguo Chen, Jingjin Hu, Yangjunna Zhang, Kejun Cheng, Ye Jin, Xuefeng Qu   +12 more
wiley   +1 more source

Exploring the Nutraceutical Potential of Achillea millefolium L.: Phytochemical Composition, Biological Activities, and Industrial Applications

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Achillea millefolium Linn., commonly known as yarrow, is an extraordinary medicinal plant. A. millefolium has broad therapeutic potential due to its phytochemistry and essential oil composition. It possesses pharmacological properties, including antidiabetic, antioxidant, anti‐inflammatory, liver‐protective, antimicrobial, and gastroprotective effects,
Tooba Majeed, Muhammad Tauseef Sultan, Ahmad Mujtaba Noman, Hassan Raza, Hagar M. Mohamed, Nimra Anees, Muhammad Imran, Muzzamal Hussain, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Entessar Al Jbawi, Ehab M. Mostafa, Samy Selim, Ayman Salama, Mohamed A. Abdelgawad   +14 more
wiley   +1 more source

The acute and dermal toxicity of antiparasitic salt briquettes on laboratory animals

Российский паразитологический журнал, 2016
The acute toxicity of salt briquettes with ivermectin is investigated. LD50 for white rats is 6400 mg/kg, white mice – 10300 mg/kg (8945÷10854). At drawing on the intact leather (skin) of rats LD50 makes more than 12500 mg/kg.
N. B. Yemelyanova
doaj  

Development and Optimization of a Nanophytosomes‐Based Thermogel as a Topical Anti‐Psoriatic for Increased Solubility and Bioavailability

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Schematic illustration of the development, optimization, and therapeutic evaluation of the Leucas aspera phytosome‐based thermogel for topical antipsoriatic therapy, highlighting its enhanced solubility, skin deposition, and in vivo efficacy in an imiquimod‐induced psoriasis model. Created with BioRender.com.
Ananda Kumar Chettupalli, Thatipally Rajeshwar, Sarad Pawar Naik Bukke   +2 more
wiley   +1 more source

Safety Assessment of Ayurvedic Formulation “Annabedi chendooram” in Experimental Animals

Ancient Science of Life
Background: Annabhedī cendūram is a classical preparation that has been used since ancient times for anemia in Ayurvedic/Siddha practice. The safety profile of the compound in experimental animals has not been established completely.
Sudesh N. Gaidhani, N. Srikanth, Arjun Singh, P. V. Deshmukh, Viswanth Reddy, Gandhidas S. Lavekar, Srikanth Ala   +6 more
doaj   +1 more source

Perbandingan Pemberian Brodifakum Ld50 Dan Ld100 Terhadap Perubahan Gambaran Histopatologi Usus Halus Tikus Wistar [PDF]

, 2016
Background : Brodifacoum is an anticoagulant substance which usually used as pest control, but this substance has a poisoning effect the body. Brodifacoum is absorbed through gastrointestinal tract which can cause the disorder of blod clotting by slowing
Dhanardhono, T. (Tuntas), Bhima, S. K. (Sigit), Al Ayoubi, Alfian Salahudin   +2 more
core