Results 151 to 160 of about 61,903 (248)

Sesquiterpene‐Rich Essential Oil From Magnolia officinalis Stem Bark: Chemical Composition, Biological Activities, and In Silico Approach

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The essential oil from Magnolia officinalis (M. officinalis) stem bark, rich in sesquiterpenes, exhibited multiple bioactivities including cytotoxic, antioxidant, α‐glucosidase inhibitory, anti‐inflammatory, and antimicrobial effects, which were further supported by molecular docking analysis.
Nguyen Thi Kim Thanh   +8 more
wiley   +1 more source

N‐(1H‐Indazolyl) Aryl Sulfonamide Hybrids as Potential Dihydropteroate Synthase Inhibitors: In Vitro Antibacterial Activity Against Escherichia coli and Staphylococcus aureus and Computational Modeling

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Sixteen indazole–sulfonamide hybrids exhibit species‐dependent antibacterial activity against E. coli and S. aureus, with the lead compound displaying an eightfold lower MIC than sulfathiazole against E. coli. Molecular docking against wild‐type and Sul1‐resistant dihydropteroate synthase identifies a candidate retaining binding affinity toward the ...
Romaisaa Boudza   +8 more
wiley   +1 more source

Antitumoral efficacy of silver nanoparticles reduced with β-D-glucose on a canine transmissible venereal tumor cell line. [PDF]

open access: yesFront Vet Sci
Estrada NP   +7 more
europepmc   +1 more source

GC–MS‐Based Phytochemical Profiling and Integrated Evaluation of Antioxidant, Antibacterial, and In Silico Studies of Kumaun Himalayan Strobilanthes Species

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Himalayan Strobilanthes species: phytochemical profiling, bioactivities, and In silico Studies. ABSTRACT Five Strobilanthes species indigenous to the Kumaun Himalayan region of Uttarakhand, India, have been historically employed in traditional medicine to treat bacterial infections, inflammatory conditions, and respiratory ailments, but remain largely ...
Sakshi Negi   +12 more
wiley   +1 more source

Exploring the Anticancer Potential of Novel Piperidine‐Embedded Isoxazol–Triazole Conjugates Against MCF‐7 Human Breast Adenocarcinoma Cell Line: Design, Synthesis, In Silico, and In Vitro Investigations

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Novel piperidine–embedded isoxazol–triazole conjugates (6a‐6o) were designed, synthesized, and evaluated for anticancer activity against MCF‐7 breast cancer cells, with selectivity assessed using noncancerous HEK293 cells. Compound 6m showed the most potent antiproliferative activity (GI50 < 10 µg/mL; SI > 5), comparable to doxorubicin, highlighting ...
Jay R. Ghonia   +2 more
wiley   +1 more source

Novel Pyrazoline Derivatives as Therapeutic Candidate for Alzheimer's Disease: An Integrated Network Pharmacology and 3D-QSAR Modelling. [PDF]

open access: yesBioinform Biol Insights
Hossain MM   +8 more
europepmc   +1 more source

Exploring the Multitarget Pharmacological Potential of Halogeton sativus Secondary Metabolites: An Integrated Experimental and Computational Approach

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Halogeton sativus is investigated through phytochemical isolation, biological evaluation, molecular dicking, molecular dynamics simulation, and ADMET prediction. The identified metabolites exhibit promising antioxidant, anti‐inflammatory, antimicrobial, and antidiabetic activities, while computational analyses provide mechanistic insights and favorable
Abd Elbasset Tamersit   +12 more
wiley   +1 more source

Metabolic and Gut Microbiome Responses to Paraquat Exposure in <i>Apis mellifera</i> Under Laboratory Conditions. [PDF]

open access: yesInsects
Mills N   +11 more
europepmc   +1 more source

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