Results 41 to 50 of about 57,088 (258)
Hemorrhagic Activity and Hemostatic Alterations Caused by Cerastes cerastes and Daboia mauritanica: Indicators of Viper Bite Severity in Morocco [PDF]
BIO Web of ConferencesSnakebite envenoming is a major global public health problem, causing approximately 5 million bites and 150,000 deaths each year, particularly in North Africa, where viper bites lead to significant morbidity and mortality.
Mesmoudi Nihal +5 more
doaj +1 more source
Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis
Advanced Science, EarlyView.Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang +16 more
wiley +1 more source
Electronic Journal of Plant Breeding, 2022 The present study was conducted to determine the mutagenic effectiveness, efficiency and lethal dose of gamma rays in papaya varieties CO7, Arka Prabhath and Arka Surya. Papaya seeds were exposed to various doses of gamma rays (0Gy, 100Gy, 150Gy, 200Gy,
Aiswarya Ravi1*, M. S. Aneesa Rani2, J. Auxcilia3, V. Thiruvengadam4 and G. Karthikeyan5
doaj +1 more source
Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective
Advanced Science, EarlyView.Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok +4 more
wiley +1 more source
Gamma radiosensitivity study on wheat (Triticum turgidum ssp. durum)
Open Agriculture, 2020 Fifty wheat seed variety (var.) CIRNO C2008 were gamma irradiated with 100, 200, 300, 400, 500, or 600 Gy by using a Cobalt-60 source at 907.39 Gy/h, and the nonirradiated seeds were considered the control (M0).
Ahumada-Flores Sergio +6 more
doaj +1 more source
Estimation of LD50 by moving averages [PDF]
Journal of Hygiene, 1952 Methods of graduation of a series of observations by means of moving averages were discussed by Sheppard (1914), and subsequently by Sherriff (1920) and a number of other writers. These methods based on least squares or weighted least squares solutions differ from actuarial or summation methods.
openaire +2 more sources
LD50 Demo Kit - Danger Adult/Child Liquid
, 2021 Glass jars from an LD50 Demo Kit that contains red dyed vegetable oil to represent a liquid formulated pesticide. These jars visually represents an oral LD50 of 50mg/kg for a 160 lb adult (left) and a 55 lb child (right), which would have a signal word ...
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Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity
Advanced Science, EarlyView.Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai +7 more
wiley +1 more source
LD50 Demo Kit - Caution Child Both
, 2021 Glass jars from an LD50 Demo Kit that contain salt to represent a dry formulated pesticide and red dyed vegetable oil to represent a liquid formulated pesticide.
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AIChE Journal, EarlyView.Abstract Transformer‐based molecular models pretrained on SMILES strings demonstrate strong performance in property prediction. However, these model often lack explicit integration of molecular surface charge distributions that govern intermolecular interactions such as hydrogen bonding and polarity.
Tae Hyun Kim +2 more
wiley +1 more source