Results 41 to 50 of about 46,156 (210)

Acute oral toxicity evaluation of Hridayarnava Rasa (A Herbo-Mineral Ayurvedic Formulation) prepared from aśodhita and śodhita tāmra bhasma

Ancient Science of Life, 2018
Background: Herbo-mineral preparations used in Ayurveda are seen as a matter of concern nowadays; especially for containing metals such as mercury, lead, and copper.
Chandrashekhar Yuvaraj Jagtap, Mukesh Nariya, Vinay J Shukla, Pradeep Kumar Prajapati   +3 more
doaj   +1 more source

Nutraceutical Benefits of Anchomanes difformis Rhizome and Its Effects on Blood Glucose and Hepatorenal Function in Normoglycemic Rats

Food Chemistry International, EarlyView.
Scientific analysis of Anchomanes difformis roots confirms significant nutraceutical potential, containing high levels of carbohydrates, proteins, and essential minerals. Phytochemical screening revealed antioxidants such as phenols and flavonoids, and although the extracts effectively lowered plasma glucose, safety testing showed dose‐dependent risks.
Lawrence Folorunso Dada, Kingsley Omage, Marshall Arebojie Azeke   +2 more
wiley   +1 more source

Uji Toksisitas Akut Dermal Gel Antioksidan Topikal C-4-Hidroksi-3-Metoksifenilkaliks[4] Resorsinarena Secara In Vivo Pada Tikus Wistar

Jurnal Penelitian Pendidikan, Psikologi dan Kesehatan
Pemberian antioksidan topikal merupakan cara yang efektif untuk melindungi kerusakan kulit yang disebabkan oleh sinar ultraviolet. Senyawa C-4-hidroksi-3-metoksifenilkaliks[4]-resorcinarene telah diteliti aktivitas antioksidannya, tabir surya, dan ...
Wade Marlinda, Eti Nurwening Sholikhah, Tri Murini   +2 more
doaj   +1 more source

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

Interdisciplinary Medicine, EarlyView.
In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang, Fan Zou, Mingdong Wang, Chenyue Wu, Yingwei Xie, Yongjun Quan, Wei Yan, Yupeng Zheng, Lianhua Li, Yuexin Liu, Jian Yu, Hao Ping   +11 more
wiley   +1 more source

Biocontrol of the pine processionary moth Thaumetopoea pityocampa (Denis and Schiffermuller, 1775) with plant extracts

Arxius de Miscel-lània Zoològica, 2019
Control biològic de la papallona de la processionària del pi Thaumetopoea pityocampa (Denis i Schiffermuller, 1775) mitjançant diversos extractes vegetals La finalitat del present estudi és oferir alternatives amb bioinsecticides elaborats a partir de
M. Kherroubi,, F. Mouhouche, Z. Zerrouk Izzeddine, M. Chahbar   +3 more
doaj   +1 more source

THE EFFECT OF DIFFERENT DOSES OF GAMMA IRRADIATION ON THE ECHIS COLORATUS VENOM TOXICITY IN MICE [PDF]

Journal of the Egyptian Society of Parasitology, 2019
Snake venoms are complex mixtures of proteins and non proteins components. This study evaluated the toxicity effect of LD50 of native Echis coloratus venom and the LD50 of dry venom irradiated with different doses of gamma radiation (2, 5 & 10 KGy ...
SAMAH MOHAMED, OSAMA ABBAS, LAMIAA SHAKER, MOHAMED MAGED, ANDREW GABRA   +4 more
doaj   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

Pharmacokinetics and Acute Safety Evaluation of Tryptanthrin, A Bioactive Constituent of Indigo naturalis, Following Intravenous Administration in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The use of Indigo naturalis in treating inflammatory diseases is clinically restricted by severe adverse events, including pulmonary arterial hypertension and hepatotoxicity. Tryptanthrin, a major indoloquinazoline alkaloid of Indigo naturalis, exhibits potent anti‐inflammatory activity; however, its specific safety profile relative to the ...
Hyung Jin Kim, Gabsik Yang, Jun Ho Lee
wiley   +1 more source

Determination of Median Lethal Dose of Carbamate Insecticides Bendiocarb and Carbaryl in Garden Lizard, Calotes versicolor [PDF]

Journal of Stress Physiology & Biochemistry
Acute lethality usually determined as LD50 is defined as median dose predicted to kill 50 percent of a given test population. LD50 is a statistical estimate of the number of milligram of toxicant per kilo gram of body weight administered by any of the ...
Anisha, Tumul Singh
doaj  

Acute toxicity of antiparasitic selamectin-based drug

Российский паразитологический журнал
The purpose of the research is to evaluate some toxicological parameters of antiparasitic selamectin-based drug.Materials and methods. The study drug is a solution for external use, 1 mL of which contains the active component selamectin (120 mg), as well
D. V. Kadyrova
doaj   +1 more source