Results 21 to 30 of about 46,156 (210)

Acute Toxicity Test of Pigeon Pea Leaves Extract (Cajanus cajan) in Rats [PDF]

open access: yesE3S Web of Conferences, 2020
Acute toxicity test was conducted to evaluate the safety level of pigeon pea (Cajanus cajan) leaves extract, using the Organisation for Economic Co-operation and Development (OECD 423) guideline method.
Wresdiyati Tutik   +4 more
doaj   +1 more source

A Novel Drug Delivery Carrier Comprised of Nimodipine Drug Solution and a Nanoemulsion: Preparation, Characterization, in vitro, and in vivo Studies

open access: yesInternational Journal of Nanomedicine, 2020
Saixu Huang, 1–3,* Zhiyong Huang, 1–3,* Zhiqin Fu, 3,* Yamin Shi, 3, 4 Qi Dai, 1, 2 Shuyan Tang, 3 Yongwei Gu, 3 Youfa Xu, 3 Jianming Chen, 3, 4 Xin Wu, 3 Fuzheng Ren 1, 2 1Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East
Huang S   +10 more
doaj  

ACUTE TOXICITY OF SUPRAMOLECULAR ANTHELMINTIC COMPLEXES OF FENBENDAZOLE DEVELOPED BY CHEMICAL MECHANICAL TECHNOLOGY USING THE DRUG DELIVERY SYSTEM

open access: yesРоссийский паразитологический журнал, 2016
Objective of research: studying of acute toxicity of supramolecular complexes of Fenbendazole developed using chemical mechanical technology in comparison with the substance of preparation injected to the stomach of white mice and rats.
A. I. Varlamova   +3 more
doaj   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

Mutagenic effectiveness, efficiency and dose optimization of gamma rays in papaya (Carica papaya L.) varieties

open access: yesElectronic Journal of Plant Breeding, 2022
The present study was conducted to determine the mutagenic effectiveness, efficiency and lethal dose of gamma rays in papaya varieties CO7, Arka Prabhath and Arka Surya. Papaya seeds were exposed to various doses of gamma rays (0Gy, 100Gy, 150Gy, 200Gy,
Aiswarya Ravi1*, M. S. Aneesa Rani2, J. Auxcilia3, V. Thiruvengadam4 and G. Karthikeyan5
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

Gamma radiosensitivity study on wheat (Triticum turgidum ssp. durum)

open access: yesOpen Agriculture, 2020
Fifty wheat seed variety (var.) CIRNO C2008 were gamma irradiated with 100, 200, 300, 400, 500, or 600 Gy by using a Cobalt-60 source at 907.39 Gy/h, and the nonirradiated seeds were considered the control (M0).
Ahumada-Flores Sergio   +6 more
doaj   +1 more source

Real‐Time and Non‐Invasive Detection of Respiratory Viral Infections Using an Intelligent Odor Monitoring System (IOMS)

open access: yesAdvanced Science, EarlyView.
An intelligent odor monitoring system integrates an IVC animal model, gas sensor array, real‐time resistance readout, and machine‐learning analysis to continuously monitor infection‐associated odor changes. The platform captures longitudinal sensor responses, distinguishes infected from healthy states, and supports early‐stage respiratory viral ...
Yajie Shen   +17 more
wiley   +1 more source

Estimation of LD50 by moving averages [PDF]

open access: yesJournal of Hygiene, 1952
Methods of graduation of a series of observations by means of moving averages were discussed by Sheppard (1914), and subsequently by Sherriff (1920) and a number of other writers. These methods based on least squares or weighted least squares solutions differ from actuarial or summation methods.
openaire   +2 more sources

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

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