Results 81 to 90 of about 93,186 (232)

In Vitro Consequences of Electronic-Cigarette Flavoring Exposure on the Immature Lung. [PDF]

, 2019
Background: The developing lung is uniquely susceptible and may be at increased risk of injury with exposure to e-cigarette constituents. We hypothesize that cellular toxicity and airway and vascular responses with exposure to flavored refill solutions ...
Berkelhamer, Sara, Goniewicz, Maciej, Gugino, Sylvia, Helman, Justin, Lakshminrusimha, Satyanarayana, Leigh, Noel   +5 more
core   +2 more sources

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

ChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz, Rubel Hasan, Mst Muslima Khatun, Mokammel Hossain Tito, Md Shadin, Ranjit Chakma, Mohammed Asiri, Faisal H. Altemani, Abdullah H. Altemani, Md Shimul Bhuia, Muhammad Torequl Islam   +10 more
wiley   +1 more source

Acute toxicity effects of ethylene glycol on lethal dose 50 (LD50), urine production, and histopathology change renal tubule cell in mice

Open Veterinary Journal
Background: The LD50 (lethal dose causing 50% mortality) of ethylene glycol (EG) and its associated toxicity in mice (Mus musculus) were assessed by evaluating kidney function. Aim: This study aimed to determine the acute toxicity of oral lethal dose
Dewa Ketut Meles, Imam Mustofa, Wurlina Wurlina, Clarissa Audreylea Donova, Essi Rayareswari Hidayanti, Niluh Suwasanti, Zulfi Nur Amrina Rosyada, Aswin Rafif Khairullah, Adeyinka Oye Akintunde, Rheza Imawan Mustofa, Satriawan Wedniyanto Putra, Riza Zainuddin Ahmad, Wasito Wasito, Ricadonna Raissa   +13 more
doaj   +1 more source

Susceptibility of selected murine and microtine species to infection by a wild strain of Francisella tularensis subsp. holoarctica

Veterinární Medicína, 2009
The purpose of this study was to compare susceptibility of BALB/c mice, common voles (Microtus arvalis) and yellow-necked mice (Apodemus flavicollis) to infection by a virulent Francisella tularensis subsp. holarctica strain.
H. Bandouchova, J. Sedlackova, M. Hubalek, M. Pohanka, L. Peckova, F. Treml, F. Vitula, J. Pikula   +7 more
doaj   +1 more source

Biological Parameters and the Acute LD50 Test

Journal of AOAC INTERNATIONAL, 1976
Abstract The acute LD50 is an inadequate index of toxicity because the catastrophe of death obscures the mechanisms and sites of action. Thus, nonlethal toxicity is not evaluated, and the LD50 is not extrapolated to the possible effects of low level exposures for long periods of time.
F, Sperling, J L, McLaughlin
openaire   +2 more sources

Effects of Clostridium perfringens iota toxin in the small intestine of mice [PDF]

, 2017
Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme.
Bruzzone, Octavio Augusto, Cangelosi, Adriana, Dailoff, Gabriela Cecilia, Díaz Carrasco, Juan María, Fernandez Miyakawa, Mariano Enrique, Geoghegan, Patricia, Leiva, Carlos Leónidas, Redondo, Enzo Alejandro, Redondo, Leandro Martin   +8 more
core   +1 more source

Computational Study on Potentially Active Antibacterial Compounds in Secondary Metabolites of Extremophilic Microorganisms

ChemistryOpen, EarlyView.
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li, Yanni Wang, Yinhuan Huang, Hui Zhou, Xiaoyun Xia, Wei Huang, Chaojie Wang   +6 more
wiley   +1 more source

Use of embryogenic cell suspensions and 60Co source gamma radiationduring in vitro mutagenesis in banana cv. ‘Manzano’ (Musa AAB)

Biotecnología Vegetal, 2021
The in vitro induction of mutations combined with somatic embryogenesis increases the efficiency of mutagenic treatments. This work was carried out with the aim of determining the effect of 60Co source Gamma radiation on embryogenic cell suspensions of ...
Claudia Beatriz Rodríguez Sierra, Idalmis Bermúdez-Caraballoso, Mayelin Rodríguez, Maritza Reyes, Leonardo Rivero Quintana   +4 more
doaj  

Female Scent Signals Enhances Male Resistance to Influenza [PDF]

, 2009
Scent of receptive females as signal to reproduction stimulate male mice to olfactory search of a potential breeding partner^1, 2^. This searching behavior is coupled with infection risk due to bacterial contamination of the fecal and urine scent marks^4^
Alla M. Zaidman, Ekaterina A. Litvinova, Elena P. Goncharova, Marina A. Zenkova, Mikhail P. Moshkin   +4 more
core   +1 more source

Heroin-piracetam mixture: suggested mechanisms of action and risks of misinterpretation for drug users [PDF]

, 2017
Piracetam is a positive allosteric modulator of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor that has been frequently used in the treatment of cognitive disorders.
Cappelletti, Simone, Ciallella, Costantino, Lombardo, Francesco, Vallone, Giuseppe, Vitale, Pasquale   +4 more
core   +1 more source