Interactions of LDL and modified LDL with mesangial cells and matrix
Kidney International, 1992 Hyperlipidemia may play a role in the progression of diabetic and other renal diseases. Low density lipoprotein (LDL) and other proteins including extracellular matrix components undergo nonenzymatic glycation in vivo. We examined the effects of glycation of LDL as occurs in diabetes (4 to 8%) on binding and uptake by mesangial cells and their ...
Vincent A. Rifici +5 more
openaire +3 more sources
The 1(st) and the 2(nd) Italian Consensus Conferences on low-density lipoprotein-apheresis. A practical synopsis and update [PDF]
, 2016 The clinical indications and guidelines for low-density lipoprotein (LDL)-apheresis set by the 1(st) Italian Consensus Conference held in Ostuni in 1990 and completed in 1992, but never published, are reported schematically.
Stefanutti, Claudia
core +1 more source
Myocardial Infarction, Stroke, and All-Cause Mortality according to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study [PDF]
Diabetes & Metabolism Journal, 2022 Background We assessed the myocardial infarction (MI), stroke, and all-cause death risks during follow-up according to the low-density lipoprotein cholesterol (LDL-C) levels among older adults.
You-Bin Lee +10 more
doaj +1 more source
Clinical Chemistry, 2018 BACKGROUND The European Atherosclerosis Society-European Federation of Clinical Chemistry and Laboratory Medicine Consensus Panel aims to provide recommendations to optimize atherogenic lipoprotein quantification for cardiovascular risk management ...
M. Langlois +21 more
semanticscholar +1 more source
Systematic review and network meta-analysis on the efficacy of evolocumab and other therapies for the management of lipid levels in hyperlipidemia [PDF]
, 2017 Background: The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors evolocumab and alirocumab substantially reduce low‐density lipoprotein cholesterol (LDL‐C) when added to statin therapy in patients who need additional LDL‐C reduction ...
Bray, Sarah +13 more
core +1 more source
Mutiara Medika, 2015 Hiperkolesterolemia terjadi jika kadar kolesterol melebihi batas normal. Belimbing wuluh mempunyai banyak kandungan senyawa yang dibutuhkan manusia diantaranya pektin. Pektin mempunyai peranan dalam menurunkan kadar kolesterol.
Dedy Sukmo Anggoro, Yoni Astuti
doaj +1 more source
Nature Communications, 2016 Despite widespread use of statins to reduce low-density lipoprotein cholesterol (LDL-C) and associated atherosclerotic cardiovascular risk, many patients do not achieve sufficient LDL-C lowering due to muscle-related side effects, indicating novel ...
Stephen L. Pinkosky +11 more
semanticscholar +1 more source
Interleukin-6 blockade raises LDL via reduced catabolism rather than via increased synthesis: a cytokine-specific mechanism for cholesterol changes in rheumatoid arthritis [PDF]
, 2017 Objectives Patients with rheumatoid arthritis (RA) have reduced serum low-density lipoprotein cholesterol (LDL-c), which increases following therapeutic IL-6 blockade. We aimed to define the metabolic pathways underlying these lipid changes.
Caslake, Muriel +6 more
core +1 more source
The major pathways of lipids (triglyceride and cholesterol) and lipoprotein metabolism
Zanco Journal of Pure and Applied Sciences, 2021 Lipids are considered as organic substances that are relatively insoluble in water while soluble in organic solvents such as alcohol and ether. Unlike carbohydrates, proteins and nucleic acids, lipids are not polymers.
Karzan Jalal Salih
doaj +1 more source
Occupational Exposure to Vegetable Oil: a Risk Factor of Blood Lipid Disorder
Journal of Environmental Health and Sustainable Development, 2021 Introduction: Few pieces of evidence are available about the association between occupational exposure to vegetable oil and the risk of blood lipid problems. This study was aimed to investigate the relationship between exposure to vegetable oil and blood
Fariborz Omidi +5 more
doaj