Results 31 to 40 of about 405,931 (255)
Up-regulated miR-106b inhibits ox-LDL-induced endothelial cell apoptosis in atherosclerosis
, 2020 This research aimed to explore the molecular mechanism of microRNA (miR)-106b in cell apoptosis of atherosclerosis (AS). Human aortic endothelial cells (HAECs) were divided into control group, oxidized-low-density lipoproteins (ox-LDL) group, miR-106b NC+
Jie Xu (34477) +4 more
core +1 more source
A correlative study of uric acid with lipid profile
Asian Journal of Medical Sciences, 2013 Objective: the study was conducted to verify the association of hyperuricemia with lipid profile in a group of Assamese people so as to take necessary precautions from developing future cardiovascular disease (CVD).
Devajit Sarmah
doaj +1 more source
LDL-C goal achievement rates among patients with dyslipidemia (based on the 2015 Korean guidelines).
, 2020 LDL-C, low-density lipoprotein cholesterol.
Siin Kim (3949709) +5 more
core +1 more source
Efficacy and Safety of Pitavastatin in a Real-World Setting: Observational Study Evaluating SaFety in Patient Treated with Pitavastatin in Korea (PROOF Study) [PDF]
Endocrinology and Metabolism, 2020 Background While randomized controlled trials provide useful information about drug safety and efficacy, they do not always reflect the observed results in the real world.
In-Kyung Jeong, Sung-Rae Kim
doaj +1 more source
PCSK9: A Key Target for the Treatment of Cardiovascular Disease (CVD) [PDF]
Advanced Pharmaceutical Bulletin, 2020 Proprotein convertase subtilisin/kexin type 9 (PCSK9), as a vital modulator of low-density lipoprotein cholesterol (LDL-C) , is raised in hepatocytes and released into plasma where it binds to LDL receptors (LDLR), leading to their cleavage.
Saeideh Sobati +6 more
doaj +1 more source
Effect of irisin on ox-LDL-induced inflammation in HUVECs.
, 2016 (A) HUVECs were exposed to different concentrations of ox-LDL (20–100 μg/mL) for 24h, and the cell viability was assessed through an MTT assay. (B) HUVECs were treated with different concentrations of irisin (10, 20, and 40 nM) with or without 80 μg/mL ...
Zheng Zhou (152309) +16 more
core +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Relationship between behcets disease and oxidant and antioxidant markers
Medicine Science, 2020 Behcets disease is known as a chronic and inflammatory vasculitis with multiple system and organ involvement. In this study, we aimed to evaluate the relationship between BD and oxidative stress by evaluating the total antioxidant status (TAS), total ...
Fikret Akyurek, Fatma Tuncez Akyurek
doaj +1 more source
, 2017 The pathogenesis of nonalcoholic steatohepatitis (NASH), like that of atherosclerosis, involves lipid accumulation, inflammation and fibrosis. Recent studies suggest that oxidized LDL (oxLDL) may be a risk factor for NASH, but oxLDL levels were not ...
Lai, Yu-Sheng;Yang, Tzu-Ching;Chang, Po-Yuan;Chang, Shwu-Fen;Ho, Shu-Li;Chen, Hui-Ling;Lu, Shao-Chun +1 more
core +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source