Results 11 to 20 of about 370,495 (313)

Altered Susceptibility to in Vitro Oxidation of LDL in LDL Complexes and LDL Aggregates [PDF]

Annals of the New York Academy of Sciences, 1992
Low density lipoprotein (LDL) is known to form complexes with polysulfated compounds, like heparin, dextran sulfate (DS), and chondroitin sulfate. In particular, chondroitin 6-sulfate (C6S)-rich proteoglycans of the arterial intima can associate with LDL, resulting in accumulation of LDL in atherosclerotic lesions.
M, Hermann, B, Gmeiner
openaire   +3 more sources

Triglycerides effect on the levels of low density lipoprotein and high density lipoprotein in type 2 diabetic patients. [PDF]

The Medical Journal of Basrah University, 2017
Background: Type 2 Diabetes mellitus is a worldwide disease with the recent changes in life styles is associated with increasing complications and hyperlipidemia is hallmark risk factor for most complications.
Ahmed Aubed Sherhan, Abdulhussen Omran
doaj   +1 more source

Intracellular transports and atherogenesis

Frontiers in Bioscience-Landmark, 2020
There is a great progress in understanding the cellular and molecular aspects of atherosclerosis, which is one of the leading causes of death. Yet, there are questions regarding the cellular and metabolic mechanisms that lead to atherogenesis.
Alexander A. Mirоnоv, Irina S. Sesorova, Ivan D. Dimov, Natalia R. Karelina, Galina V. Beznoussenko   +4 more
doaj   +1 more source

Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]

, 2008
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley, J. A. D. Wattis, Panovska, J., Byrne, H.M., Jackson, K.G., H. Blackburn, Wattis, JA, H. M. Byrne, L. Pickersgill, O'Malley, B, Panovska, J, Wattis, J.A.D., Pickersgill, L, Pickersgill, L., Blackburn, H, Byrne, HM, Byrne, Helen, K. G. Jackson, Wattis, JAD, O'Malley, B., Blackburn, H., Jackson, KG, J. Panovska   +22 more
core   +1 more source

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core   +1 more source

Electronegative LDL: A Circulating Modified LDL with a Role in Inflammation [PDF]

Mediators of Inflammation, 2013
Electronegative low density lipoprotein (LDL(−)) is a minor modified fraction of LDL found in blood. It comprises a heterogeneous population of LDL particles modified by various mechanisms sharing as a common feature increased electronegativity. Modification by oxidation is one of these mechanisms. LDL(−) has inflammatory properties similar to those of
Montserrat Estruch, José Luis Sánchez-Quesada, Jordi Ordóñez Llanos, Sònia Benítez   +3 more
openaire   +5 more sources

Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin [PDF]

, 2010
OBJECTIVE The aim of this study was to investigate whether apolipoprotein B100 of LDL suffers increased damage by glycation, oxidation, and nitration in patients with type 2 diabetes, including patients receiving metformin therapy.
Rabbani, Naila, D. Zehnder, A. Ceriello, P. J. Thornalley, N. Rabbani, Zehnder, Daniel, Chittari, Madhu Varma, C. W. Bodmer, Bodmer, Charles W., Ceriello, Antonio, M. V. Chittari, Thornalley, Paul J.   +11 more
core   +1 more source

LDL-C target attainment in the total cohort and stratified by risk as observed and simulated.

, 2022
LDL-C concentrations are given as median (interquartile range). LDL-C: Low-density lipoprotein cholesterol. LLT: Lipid-lowering therapy.
Aikaterini Bilitou (5785471), Ulrich Laufs (360751), Christian Becker (49615), Julius L. Katzmann (10960479)   +3 more
core   +1 more source

Cinnamon effects on blood pressure and metabolic profile: A double-blind, randomized, placebo-controlled trial in patients with stage 1 hypertension [PDF]

Avicenna Journal of Phytomedicine, 2021
Objective: Cinnamon effect on blood pressure remains controversial. The present pilot study assessed cinnamon effect on blood pressure, and metabolic profile of stage 1 hypertension patients (S1HTN).
Fatemeh Shirzad, Negar Morovatdar, Ramin Rezaee, Konstantinos Tsarouhas, Alireza Abdollahi Moghaddam   +4 more
doaj   +1 more source

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins [PDF]

, 2014
Statins effectively lower LDL cholesterol levels in large studies and the observed interindividual response variability may be partially explained by genetic variation.
Herrington, D.M., Postmus, Iris, Trompet, S., Ridker, P.M., O'Donnell, C.J. (Christopher J.), Ballantyne, C. (Christie), Liu, YM, Kastelein, JJP, Rivadeneira Ramirez, F. (Fernando), Pearson, Richard, Arnold, A.M. (Alice), O???donnell, Christopher J., Palmer, Colin N.A., Boerwinkle, E., Wei, W.-Q. (Wei-Qi), Barnes, M.R., Viswanathan, Ananth C., Potter, S.C. (Simon), Arnold, A.M., Caulfield, M. (Mark), Groop, L, Viswanathan, A.C. (Ananth), McKeigue, Paul M., Eiriksdottir, Gudny, Pirinen, M. (Matti), Palmer, Colin N. A., Barratt, BJ, Edkins, Sarah, Waller, Matthew, Smith, AV, Whitsel, E.A. (Eric), de Keyser, Catherine E., Buckley, BM, Arsenault, B.J. (Benoit J.), Whitsel, E.A., Hammond, Naomi, Sever, P, Franco Duran, OH, Liu, Y, Corvin, A. (Aiden), Palmer, CN, Barratt, B.J., Liu, Ching-Ti, Kastelein, J.J.P. (John), Groop, L., Macfadyen, JG, de Keyser, Toke, Zhou, Kaixin, Ford, I, Trompet, S. (Stella), Su, Zhan, Boerwinkle, Eric, Chu, A.Y., Sotoodehnia, Nona, Franco, O.H., Band, G. (Gavin), Wiggins, Kerri L., Eiriksdottir, G, O'Donnell, CJ, Chen, Y.-D. Ida, Boerwinkle, E, Uitterlinden, AG, Potter, Simon C., Heckbert, Susan R, Feng, Q. (Qiping), Hofman, A., Bis, JC, Krauss, Ronald M., Nickerson, D.A. (Deborah), Harris, T.B. (Tamara), Evans, DS, Palmer, C.N.A. (Colin), Blackburn, H. (Hannah), Stanton, A. (Alice), Wood, N.W. (Nicholas), Tardif, J-C, Wiggins, K.L. (Kerri), Johnson, A.D. (Andrew), Giulianini, F., Jukema, JW, Kritchevsky, S.B., Munroe, PB, Pierre Dubé, Marie, Cupples, L.A. (Adrienne), Blackwell, K.L. (Kimberly), Griffin, P., Keyser, C.E. de, Pirinen, Matti, Morris, A., Sattar, N, Rivadeneira, F, Griffin, P. (Paula), Shields, Denis C., Herrington, DM, Hellenthal, Garrett, Plomin, R. (Robert), Stafford, J.M. (Jeanette M.), Bellenguez, C??line, Betteridge, J, Shields, D.C., Widaa, S. (Sara), Stürmer, Til, Hitman, G, Wiggins, K.L., Bumpstead, Suzannah J., Hovingh, G.K., Neil, A. (Andrew), Tardif, J.-C. (Jean-Claude), Lumley, T., O'Brien, E. (Eoin), Munroe, P. (Patricia), ?, ?, de Craen, AJM, Liu, C-T, Wiggins, KL, Ford, Ian, De Craen, AJ, O’Donnell, Christopher J., Stafford, Jeanette M., Sotoodehnia, N. (Nona), McCarthy, MI, Bramon, E. (Elvira), Slagboom, PE, Casas, J.P. (Juan), Neil, Andrew, MacFadyen, J.G. (Jean G.), Shields, D.C. (Denis C.), Taylor, KD, Doney, A., Wei, Wei-Qi, Adrienne Cupples, L, Wilke, RA, Taylor, K.D., Strange, A. (Amy), Spencer, Chris C.A., McCann, O.T. (Owen), Morris, Andrew, Welcome Trust Case Control Consort, Postmus, D. (Douwe), Emilsson, V., Freeman, Colin, Launer, L.J., Guo, Xiuqing, Spencer, Chris C. A., Avery, C.L., Cupples, L.A., Rice, Kenneth, Krauss, RM, Gray, Emma, Chasman, Daniel I., Sever, P. (Peter), Caulfield, M.J., Li, G. (Guo), O'Brien, Eoin, Franco, OH, Gudnason, V. (Vilmundur), other, and, Sotoodehnia, N, Nickerson, D.A., Jayakumar, A. (Alagurevathi), Boekholdt, S.M., Chu, AY, Uitterlinden, Andr?? G., Wilke, R.A. (Russell A.), Doney, Alex; id_orcid, Li, XH, Sun, FG, Colhoun, HM, MacFadyen, J.G., Chasman, Daniel, Avery, CL, Rice, K., Betteridge, John, Carr, F, Durrington, P.N. (Paul), Ngwa, JS, Buckley, B.M., Post, Wendy, Deshmukh, H.A., Herrington, D.M. (David), Liu, C.-T. (Ching-Ti), Giulianini, F. (Franco), Munroe, Patricia B., Hammond, N. (Naomi), Uitterlinden, A.G. (André), Ahlqvist, E. (Emma), Ridker, PM, Jukema, J.W., Widaa, Sara, Betteridge, J., Duncanson, A. (Audrey), Ding, JZ (Jing Zhong), Adrienne Cupples, L., Sever, Peter, Poulter, N, Zhou, K. (Kaixin), Ballantyne, C.M., Matthijs Boekholdt, S., Carr, F., Liu, CT, Stott, D.J. (David. J.), Slagboom, P.E., Morris, A.D. (Andrew), Buckley, Brendan M., Mathew, C.G. (Christopher G.), Stanton, A, Gudnason, V, Li, Xiaohui, Shaw-Hawkins, S. (Sue), O???brien, Eoin, Ding, Jingzhong, Uitterlinden, André G., Cupples, LA, Nyberg, F, Mathew, Christopher G., Wellcome Trust Case Control Consortium, Warren, Helen R., Wei, WQ, Chu, A.Y. (Audrey), Warren, H.R., Stott, D.J., Smith, Albert V., Barratt, B.J. (Bryan J.), Westendorp, Rudi G. J., Vasan, Ramachandran S., Bramon, Elvira, Plomin, Robert, Nyberg, F. (Fredrik), Hellenthal, F.A., McCarthy, M.I., Tardif, Jean-Claude, Sawcer, S.J. (Stephen), Pierre Dub??, Marie, Chen, Y-DI, Munroe, P.B., Band, Gavin, Tardif, JC, Rotter, J.I., Post, W. (Wendy), Groop, L. (Leif), Wilke, R.A., Trompet, Stella, Psaty, B.M. (Bruce), Harris, TB, Casas, Juan P., Keyser, C.E. (Catherina Elisabeth) de, Stafford, JM, Deloukas, Panos, Li, X. (Xiaohui), Herrington, David M., Neil, A, Brown, Matthew, Ida Chen, Y.-D., Bellenguez, C. (Céline), Li, Guo, Barroso, Ines, Sun, F. (Fangui), McKeigue, P.M., Launer, Leonore J., Guo, XQ, Lumley, Thomas, Kastelein, John J. P., Chu, Audrey Y., Smith, Nicholas L., Smith, A.V. (Davey), Hofman, Albert, Donnelly, L.A. (Louise), Palmer, CNA, Barnes, M.J. (Michael), Doney, A, Tardif, J.C., Postmus, I, Shaw-Hawkins, S, de Craen, Anton J. M., Stricker, Bruno H., Poulter, N.R. (Neil), Stanton, A., Liddle, J. (Jennifer), Avery, Christy L., Vasan, R.S., Su, Z. (Zhan), Barroso, I.E. (Inês), Ding, J, Colhoun, H.M. (H.), Ngwa, Julius S., Ahlqvist, E, Corvin, Aiden, Rotter, J.I. (Jerome I.), Johnson, Andrew D., Rotter, JI, Ricketts, M. (Michelle), McCarthy, M.I. (Mark), Ahlqvist, Emma, Franco, O.H. (Oscar), Trembath, R.C. (Richard), Ballantyne, Christie M., Sotoodehnia, N., Psaty, Bruce M., Wei, W-Q, Carr, Fiona, Hitman, G.A. (Graham), Liu, C.T., Feng, Q, Barnes, Michael, Smith, N.L., Caulfield, Mark J., Westendorp, RGJ, MacFadyen, Jean G., Doney, Alex, Boekholdt, SM, Gudnason, V., Deshmukh, HA, Slagboom, P.E. (Eline), Boekholdt, S.M. (Matthijs), Freeman, C. (Colin), Neil, A., Stricker, Bruno, Barnes, Michael R., Liddle, Jennifer, Whittaker, Pamela, Bis, J.C. (Joshua), Ngwa, J.S., Chasman, D.I. (Daniel), Gwilliam, R. (Rhian), Durrington, Paul N., Hofman, Bert, Denny, J.C. (Joshua C.), Jukema, J. Wouter, Johnson, A.D., Trembath, Richard, Rautanen, A. (Anna), Liu, Y. (YongMei), Mathew, Christopher G.; id_orcid, Jankowski, J.A. (Janusz Antoni), Donnelly, LA, Gwilliam, Rhian, Palmer, C.N.A., Wood, Nicholas W., Dubé, MP, Heckbert, SR, Bellenguez, Céline, Sattar, Naveed, Giannoulatou, E. (Eleni), Stott, David J., Lumley, T, Franco, Oscar H., Durrington, P.N., Deshmukh, Harshal A., De Keyser, CE, Whitsel, EA, Ahlqvist, E., Waller, M. (Matthew), Smith, A.V., Uitterlinden, André, Heckbert, S.R. (Susan), Blackwell, Jenefer M., Kritchevsky, SB, Craen, A.J. (Anton) de, Mckeigue, P.M. (Paul), Chasman, DI, Bumpstead, S. (Suzannah), Dube, M.P., Boekholdt, S. Matthijs, Feng, QiPing, Guo, X.Q., Slagboom, P. Eline, Stuermer, T, Rivadeneira, Fernando, Brown, M.A. (Matthew), Stricker, B.H.Ch. (Bruno), Edkins, T. (Ted), Blackburn, Hannah, Eiriksdottir, G. (Gudny), Smith, N.L. (Nicholas), Bis, J.C., Ravindrarajah, Radhi, Harris, T.B., Smith, J.D. (Joshua D.), Rice, K.M. (Kenneth), Barnes, MR, Wilke, Russell A., Hitman, G., Feng, QP, McCann, Owen T., Ding, J.Z., Sawcer, Stephen J., Vukcevic, D. (Damjan), Jukema, J.W. (Jan Wouter), Wouter Jukema, J, Liu, Y.M., Hitman, Graham, Strange, Amy, Li, G, Hunt, S.E. (Sarah), Eline Slagboom, P., Ding, J. (Jingzhong), Langford, C. (Cordelia), St??rmer, Til, Langford, Cordelia, Stricker, B.H., Shaw-Hawkins, S., Kastelein, JJ, Donnelly, P. (Peter), Evans, Daniel S., Deshmukh, H. (Harshal), Betteridge, J. (John), Boerwinkle, E.A. (Eric), Eiriksdottir, G., Hovingh, G. Kees, Westendorp, R.G.J., Johnson, AD, Bis, Joshua C., McCarthy, Mark I., Denny, Joshua C., Dronov, Serge, Emilsson, V. (Valur), Harris, Tamara B., Li, X, Westendorp, R.G.J. (Rudi), Warren, HR, Giulianini, Franco, Guo, X. (Xiuqing), Emilsson, Valur, Heckbert, S.R., Weston, P. (Paul), Chen, Y.D.I., Kastelein, J.J.P., Launer, LJ (Lenore), Gudnason, Vilmundur, Dronov, S. (Serge), Post, W., Vasan, RS, Poulter, Neil, Chen, YDI, Uitterlinden, André; id_orcid, Sever, P., Rivadeneira, F., Liu, Yongmei, Stanton, Alice, Kastelein, John J.P., Sattar, N. (Naveed), Gillman, M. (Matthew), Craen, A.J.M. de, Donnelly, Peter, de Craen, Anton J.M., Shaw-Hawkins, Sue, Arsenault, BJ, Postmus, I., Durrington, PN, Griffin, P, Smith, Joshua D., Smith, JD, Rice, K, Dubé, G.P. (Gregory), Spencer, C.C.A. (Chris C.), Zhou, KX, Hovingh, G.K. (Kees), O’Brien, Eoin, Gillman, Matthew, Nickerson, DA, Arsenault, B.J., Donnelly, L.A., O'Donnell, C.J., Trembath, Richard C., Warren, H. (Helen), O'Brien, E., Hofman, A. (Albert), Denny, JC, Post, W, Sattar, N., Taylor, Kent D., Ford, I., Vukcevic, Damjan, Stürmer, T., Poulter, N., Caulfield, MJ, Guo, X, Weston, Paul, Whitsel, Eric A., Colhoun, Helen M., Donnelly, Louise A., Uitterlinden, A.G., Stott, DJ, Doney, A.S.F. (Alex), Rautanen, Anna, Buckley, B.M. (Brendan M.), Deshmukh, Harshal, Jankowski, Janusz, Colhoun, H.M., Ridker, P.M. (Paul), Nyberg, Fredrik, Vasan, R.S. (Ramachandran Srini), Dubé, Marie Pierre, Emilsson, V, Krauss, R.M. (Ronald), Feng, Q.P., Arnold, Alice M., Brown, Matthew A., Psaty, BM, Arsenault, Benoit J., Zhou, K, Whittaker, P. (Pamela), Westendorp, RG, Sun, Fangui, Chen, YD, Slagboom, PE (Eline), Smith, J.D., Kritchevsky, Stephen B., Consort, WTCC, Nickerson, Deborah A., Evans, D.S. (Daniel), Smith, NL, Chen, Y.-D.I. (Ida), Taylor, K.D. (Kent), Stafford, J.M., Psaty, B.M., Griffin, Paula, Giannoulatou, Eleni, Hofman, A, Carr, F. (Fiona), Nyberg, F., Lumley, T. (Thomas), Giulianini, F, Duncanson, Audrey, Launer, L.J. (Lenore), Markus, Hugh S., Hovingh, GK, Trompet, S, Stricker, BH, Li, X.H., Ballantyne, CM, Launer, LJ, Chasman, D.I., Li, G., Kees Hovingh, G., Markus, H.S. (Hugh), Evans, D.S., Morris, A, Sun, F, Krauss, R.M., McKeigue, PM, Wei, W.Q., Jayakumar, Alagurevathi, Groop, Leif, Rotter, Jerome I., Ricketts, Michelle, Kritchevsky, S.B. (Stephen), Gray, E. (Emma), Ravindrarajah, R. (Radhi), Shields, DC, Deloukas, P. (Panagiotis), Pearson, R. (Ruth), Sun, F.G., Zhou, K.X., Denny, J.C., Hunt, Sarah E., Barratt, Bryan J., Stürmer, T, Ridker, Paul M., O'Brien, E, Arnold, AM, Palmer, Colin N. A.; id_orcid   +561 more
core   +1 more source