Results 11 to 20 of about 416,899 (301)
Altered susceptibility to in vitro oxidation of LDL in LDL complexes and LDL aggregates. [PDF]
Low density lipoprotein (LDL) is known to form complexes with polysulfated compounds, like heparin, dextran sulfate (DS), and chondroitin sulfate. In particular, chondroitin 6-sulfate (C6S)-rich proteoglycans of the arterial intima can associate with LDL,
B Gmeiner, M Hermann
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In this article, the history of the LDL receptor is recounted by its codiscoverers. Their early work on the LDL receptor explained a genetic cause of heart attacks and led to new ways of thinking about cholesterol metabolism. The LDL receptor discovery also introduced three general concepts to cell biology: receptor-mediated endocytosis, receptor ...
Joseph L, Goldstein, Michael S, Brown
openaire +2 more sources
Electronegative LDL: A Circulating Modified LDL with a Role in Inflammation [PDF]
Electronegative low density lipoprotein (LDL(−)) is a minor modified fraction of LDL found in blood. It comprises a heterogeneous population of LDL particles modified by various mechanisms sharing as a common feature increased electronegativity. Modification by oxidation is one of these mechanisms. LDL(−) has inflammatory properties similar to those of
Montserrat Estruch +3 more
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LDL-C target attainment in the total cohort and stratified by risk as observed and simulated.
LDL-C concentrations are given as median (interquartile range). LDL-C: Low-density lipoprotein cholesterol. LLT: Lipid-lowering therapy.
Aikaterini Bilitou (5785471) +3 more
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Intracellular transports and atherogenesis
There is a great progress in understanding the cellular and molecular aspects of atherosclerosis, which is one of the leading causes of death. Yet, there are questions regarding the cellular and metabolic mechanisms that lead to atherogenesis.
Alexander A. Mirоnоv +4 more
doaj +1 more source
Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley +20 more
core +1 more source
Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core +1 more source
When LDL Cholesterol Is Not LDL Cholesterol
LpX is a lipoprotein formed in cholestatic conditions and often erroneously reported as LDL-C. A low ApoB level can support the diagnosis of LpX. Treatment should not automatically focus on lowering serum lipid levels, but primarily on resolving the cause of cholestasis. (Level of Difficulty: Advanced.).
Lisa P.M. Huygen +3 more
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Drakaea Ldl. undSpiculaea Ldl [PDF]
n ...
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Cinnamon effects on blood pressure and metabolic profile: A double-blind, randomized, placebo-controlled trial in patients with stage 1 hypertension [PDF]
Objective: Cinnamon effect on blood pressure remains controversial. The present pilot study assessed cinnamon effect on blood pressure, and metabolic profile of stage 1 hypertension patients (S1HTN).
Fatemeh Shirzad +4 more
doaj +1 more source

