Results 41 to 50 of about 416,899 (301)

A correlative study of uric acid with lipid profile

open access: yesAsian Journal of Medical Sciences, 2013
Objective: the study was conducted to verify the association of hyperuricemia with lipid profile in a group of Assamese people so as to take necessary precautions from developing future cardiovascular disease (CVD).
Devajit Sarmah
doaj   +1 more source

LDL-C goal achievement rates based on the 2015 Korean guidelines and LDL-C distributions categorized by the use of lipid-modifying treatment.

open access: yes, 2020
LDL-C, low-density lipoprotein cholesterol; LMT, lipid-modifying treatment.
Siin Kim (3949709)   +5 more
core   +1 more source

Efficacy and Safety of Pitavastatin in a Real-World Setting: Observational Study Evaluating SaFety in Patient Treated with Pitavastatin in Korea (PROOF Study) [PDF]

open access: yesEndocrinology and Metabolism, 2020
Background While randomized controlled trials provide useful information about drug safety and efficacy, they do not always reflect the observed results in the real world.
In-Kyung Jeong, Sung-Rae Kim
doaj   +1 more source

PCSK9: A Key Target for the Treatment of Cardiovascular Disease (CVD) [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2020
Proprotein convertase subtilisin/kexin type 9 (PCSK9), as a vital modulator of low-density lipoprotein cholesterol (LDL-C) , is raised in hepatocytes and released into plasma where it binds to LDL receptors (LDLR), leading to their cleavage.
Saeideh Sobati   +6 more
doaj   +1 more source

Global Burden of Elevated LDL-C [PDF]

open access: yes
Importance Elevated low-density lipoprotein cholesterol (LDL-C) is a modifiable risk factor for cardiovascular disease, the leading cause of premature death worldwide.
Kwanghyun Kim   +999 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Relationship between behcet’s disease and oxidant and antioxidant markers

open access: yesMedicine Science, 2020
Behcet’s disease is known as a chronic and inflammatory vasculitis with multiple system and organ involvement. In this study, we aimed to evaluate the relationship between BD and oxidative stress by evaluating the total antioxidant status (TAS), total ...
Fikret Akyurek, Fatma Tuncez Akyurek
doaj   +1 more source

Ox-LDL-mediated repletion of ATP6V0d2-KD cholesterol levels restores PV volumes and impacts parasite multiplication.

open access: yes, 2019
A. Intracellular cholesterol levels displayed by nonsilenced or ATP6V0d2-KD macrophages treated or not with 50 μg/ml of ox-LDL for 48 hours, showing that ox-LDL replenishes the ~40% lower cholesterol amount of ATP6V0d2-KD to levels comparable to ...
Luiza Campos Reis (6843587)   +11 more
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Lipoprotein-associated phospholipase A2 in relation to lipid markers: A pan-India correlation study

open access: yesAsian Journal of Medical Sciences, 2019
Background: Conventional serum markers are routinely recommended to assess heart health. However, many new biochemical markers like lipoprotein-associated phospholipase A2 (Lp-PLA2) has been studied as an efficient cardiac risk marker.
Sandhya Iyer   +4 more
doaj   +1 more source

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