Results 41 to 50 of about 370,495 (313)
Effect of irisin on ox-LDL-induced inflammation in HUVECs.
, 2016 (A) HUVECs were exposed to different concentrations of ox-LDL (20–100 μg/mL) for 24h, and the cell viability was assessed through an MTT assay. (B) HUVECs were treated with different concentrations of irisin (10, 20, and 40 nM) with or without 80 μg/mL ...
Zheng Zhou (152309) +16 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Relationship between behcets disease and oxidant and antioxidant markers
Medicine Science, 2020 Behcets disease is known as a chronic and inflammatory vasculitis with multiple system and organ involvement. In this study, we aimed to evaluate the relationship between BD and oxidative stress by evaluating the total antioxidant status (TAS), total ...
Fikret Akyurek, Fatma Tuncez Akyurek
doaj +1 more source
, 2017 The pathogenesis of nonalcoholic steatohepatitis (NASH), like that of atherosclerosis, involves lipid accumulation, inflammation and fibrosis. Recent studies suggest that oxidized LDL (oxLDL) may be a risk factor for NASH, but oxLDL levels were not ...
Lai, Yu-Sheng;Yang, Tzu-Ching;Chang, Po-Yuan;Chang, Shwu-Fen;Ho, Shu-Li;Chen, Hui-Ling;Lu, Shao-Chun +1 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Lipoprotein-associated phospholipase A2 in relation to lipid markers: A pan-India correlation study
Asian Journal of Medical Sciences, 2019 Background: Conventional serum markers are routinely recommended to assess heart health. However, many new biochemical markers like lipoprotein-associated phospholipase A2 (Lp-PLA2) has been studied as an efficient cardiac risk marker.
Sandhya Iyer +4 more
doaj +1 more source
Monotherapy with the PCSK9 inhibitor alirocumab versus ezetimibe in patients with hypercholesterolemia:Results of a 24week, double-blind, randomized Phase 3 trial [PDF]
, 2014 Background:Efficacy and safety of alirocumab were compared with ezetimibe in hypercholesterolemic patients at moderate cardiovascular risk not receiving statins or other lipid-lowering therapy. Methods In a Phase 3, randomized, double-blind, double-dummy
Merlet, Laurence +9 more
core +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
, 2017 Admixture Mapping results for LDL-cholesterol: Mexico City sample
Esteban J Parra (7852496) +1 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source