Results 91 to 100 of about 604,324 (300)

Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study.

Journal of Lipid Research, 1994
Plasma low density lipoprotein (LDL) cholesterol, non-high density lipoprotein (HDL) cholesterol, and apolipoprotein (apo) B, the major protein constituent of LDL, were measured in 1,533 men (mean age 49 +/- 10 years) and 1,597 women (mean age 49 +/- 10 ...
E J Schaefer, S Lamon-Fava, S D Cohn, M M Schaefer, J M Ordovas, W P Castelli, P W Wilson   +6 more
doaj   +1 more source

Changes across median 12 (8–24) weeks of follow up in total cholesterol (TC), HDL cholesterol (HDL), LDL-cholesterol (LDL), LDL/HDL ratio, TC/HDL ratio and triglycerides (TG), according to diagnosis of hypercholesterolemia (HC) or hypertriglyceridemia (HT) at baseline.

, 2019
Changes across median 12 (8–24) weeks of follow up in total cholesterol (TC), HDL cholesterol (HDL), LDL-cholesterol (LDL), LDL/HDL ratio, TC/HDL ratio and triglycerides (TG), according to diagnosis of hypercholesterolemia (HC) or hypertriglyceridemia ...
Lucia Taramasso (344095), Laura Comi (7224593), Antonio Di Biagio (316138), Franco Maggiolo (372561), Elisa Di Filippo (554893), Sara Mora (7490507), Andrea Gori (62770), Federica Briano (7490504), Niccolò Riccardi (3841420), Mauro Giacomini (5725730)   +9 more
core   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Effects of lipoprotein lipase and statins on cholesterol uptake into heart and skeletal muscles⃞

Journal of Lipid Research, 2007
Regulation of cholesterol metabolism in cultured cells and in the liver is dependent on actions of the LDL receptor. However, nonhepatic tissues have multiple pathways of cholesterol uptake.
Masayoshi Yokoyama, Toru Seo, Taesik Park, Hiroaki Yagyu, Yunying Hu, Ni Huiping Son, Ayanna S. Augustus, Reeba K. Vikramadithyan, Rajasekhar Ramakrishnan, Leslie K. Pulawa, Robert H. Eckel, Ira J. Goldberg   +11 more
doaj   +1 more source

Complementary therapy to target LDL cholesterol: the role of the ezetimibe/simvastatin combination

, 2006
Ryan C Neal, Peter H JonesBaylor College of Medicine, Section of Lipid and Atherosclerosis, Houston, TX, USAAbstract: Cardiovascular (CV) disease remains the number 1 cause of death in the USA.
Ryan C Neal, Peter H Jones
core  

Cholesterol, triglycerides, high-density lipoproteins cholesterol (HDL-c), and low-density lipoproteins cholesterol (LDL-c) levels of respondents.

, 2022
Cholesterol, triglycerides, high-density lipoproteins cholesterol (HDL-c), and low-density lipoproteins cholesterol (LDL-c) levels of respondents.
Kholoud B. Alabdulkarem (12042227), Ghedeir M. Alshammari (11518408), Mohammed Abdo Yahya (12042236), Ahmad N. AlHadi (12042224), Omar Sulaiman M. Albader (12042230), Mirza B. Baig (12042233), Hind E. Aljuhani (12042221)   +6 more
core   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Quo vadis, LDL cholesterol?

Advances in Laboratory Medicine, 2023
Cobos Andrés, Valdivielso Pedro
doaj   +1 more source

Dependence on dietary cholesterol for n-3 polyunsaturated fatty acid-induced changes in plasma cholesterol in the Syrian hamster.

Journal of Lipid Research, 1992
Male Syrian hamsters consumed diets containing incremental increases in dietary n-3 fatty acids from fish oil with either low (0.015% w/w) or moderate (0.1% w/w) dietary cholesterol content.
ME Surette, J Whelan, GP Lu, KS Broughton, JE Kinsella   +4 more
doaj   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source