Results 131 to 140 of about 604,324 (300)
British Journal of Clinical Pharmacology, EarlyView.Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza +12 more
wiley +1 more source
European Medical Journal Cardiology, 2015 Background: The Lipid Regulatory Hypothesis (LRH) states that the best way to regress atherosclerotic plaque is to simultaneously decrease the cholesterol being transported into the arterial wall by low-density lipoprotein (LDL) and increase the ...
William E. Feeman, Jr +2 more
doaj
Biotechnology and Bioengineering, EarlyView.ABSTRACT Cell‐based models are highly valuable platforms for preclinical studies of atherosclerosis, offering controllable environments to investigate disease mechanisms. Three‐dimensional (3D) spheroids, a class of cell‐based models, enable the study of atherosclerotic disease phenomena under physiologically relevant yet controlled conditions. In this
Ibukunoluwa Naiyeju +2 more
wiley +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Biodegradable‐polymer (BP) drug‐eluting stents (DES) were developed to mitigate potential late adverse events related to persistent durable polymers in durable‐polymer (DP) DES; however, contemporary long‐term real‐world comparative data remain limited. Aims We aimed to compare the 5‐year clinical outcomes of contemporary BP‐DES and
Yangyoun Lee +6 more
wiley +1 more source
Forest Plots of Polypills versus Control for Change in Total Cholesterol and LDL-cholesterol.
, 2012 Forest Plots of Polypills versus Control for Change in Total Cholesterol and LDL-cholesterol.
Min Jun (109439) +7 more
core +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Flowchart of patient enrollment. ABSTRACT Background Cardiovascular disease remains a major public health burden. This study aimed to investigate the effect of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype on folic acid treatment response and cardiovascular endothelial function in patients with hyperhomocysteinemia (HHcy).
Xiaohui Dou +8 more
wiley +1 more source
Oat beta-glucan lowers total and LDL-cholesterol
, 2001 Several soluble polysaccharides have been shown to have cholesterol-lowering properties and to have a role in prevention of heart disease. Major sources of one such polysaccharide (beta-glucan) are oats and barley.
P Nestel (13299699) +3 more
core
Chronic Diseases and Translational Medicine, EarlyView.ABSTRACT Background Diabetes mellitus (DM) commonly coexists with dyslipidemia and elevated cardiovascular risk. Food‐based interventions containing antioxidants and polyphenols may support lipid metabolism. This study evaluated the short‐term effects of Golden Rice cookies enriched with active Piper crocatum extract on lipid profiles in adults with DM.
Altje Suwardi Abram +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Low‐dose aspirin is no longer routinely recommended for the primary prevention of cardiovascular disease in older adults due to a lack of net benefit over bleeding risk. We hypothesized that genetic subgroups may experience differential harm or benefit from aspirin therapy.
Peter D. Fransquet +8 more
wiley +1 more source