Results 141 to 150 of about 604,324 (300)
The E3 ubiquitin ligase c-IAP1 regulates PCSK9-mediated LDLR degradation: Linking the TNF-α pathway to cholesterol uptake [PDF]
, 2010 Proprotein convertase subtilisin/kexin type 9 (PCSK9), in addition to LDLR (low-density lipoprotein receptor) and APOB (apolipoprotein B), is one of three loci implicated in autosomal dominant hypercholesterolaemia (ADH)^1^.
Lizhi Liu, Weiming Xu
core
Impact of Food and Beverage on Enlicitide Pharmacokinetics and LDL‐C Lowering
Clinical Pharmacology &Therapeutics, EarlyView.Enlicitide decanoate is a macrocyclic peptide first‐in‐class oral PCSK9 inhibitor that lowers LDL‐C, with maximal efficacy achieved when administered on an empty stomach. This work characterizes the effects of food, pre‐dose fasting duration (2–8 hours), water volume, common beverages (black coffee and plain tea), and other real‐world scenarios on ...
Douglas G. Johns +22 more
wiley +1 more source
Direct measurement of LDL cholesterol [PDF]
Clinical Chemistry, 1996 S S, Levinson, J J, Maciejko
openaire +2 more sources
VLDL-cholesterol, LDL-cholesterol and HDL-cholesterol.
, 2015 Plasma concentration of VLDL-cholesterol (Fig 2a), LDL-cholesterol (Fig 2b) and HDL-cholesterol (Fig 2c) in week 1 p.p., and before (week 0) and after (week 3) feed restriction in mid-lactation.
Evelyne C. Kessler (748451) +3 more
core +1 more source
Drug Testing and Analysis, EarlyView.This proof‐of‐concept study evaluated the impact of short‐distance drone transport on anti‐doping sample integrity compared with traditional car transport. Targeted assays and untargeted metabolomics revealed equivalent biological profiles between methods, confirming that drone delivery preserves sample integrity for the athlete biological passport ...
I. Al‐Mohannadi +13 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective To evaluate the feasibility of a randomized pilot trial of group‐based cognitive behavioral therapy (CBT) for binge eating disorder (BED) in individuals with type 2 diabetes, and to estimate exploratory clinical outcomes to inform the design of a future efficacy trial. Method Thirty‐four participants with type 2 diabetes and BED were
Pernille Fiil Nybo +4 more
wiley +1 more source
Palm oil and LDL cholesterol [PDF]
The American Journal of Clinical Nutrition, 2011 openaire +2 more sources
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1141-1150, April 2025.Abstract Background Arterial stiffness is a crucial factor in determining an increase in systolic blood pressure and pulse pressure and can also predict the development of cardiovascular disease (CVD). The purpose of this study was to examine the relationship between arterial stiffness and future CVD.
Susan Darroudi +10 more
wiley +1 more source