Results 141 to 150 of about 965,123 (374)

Low density lipoprotein from humans supplemented with n-3 fatty acids depresses both LDL receptor activity and LDLr mRNA abundance in HepG2 cells.

Journal of Lipid Research, 1992
Fish oil supplementation in humans is often associated with an expanded low density lipoprotein (LDL) pool that is not thought to reflect increased production.
S Lindsey, A Pronczuk, KC Hayes
doaj   +1 more source

Effect of diet, statin, and ômega-3 fatty acids on the blood pressure and lipidemia in humans [PDF]

, 2009
As doenças cardiovasculares são responsáveis pela alta taxa de mortalidade nos países desenvolvidos e em desenvolvimento, assim, têm sido alvo de vários estudos.
DENARDI, Daniela Cristiane Ferrari, MOREIRA, Renê, SALGADO, Jocelem Mastrodi   +2 more
core   +2 more sources

The ABC (HbA1c, blood pressure and LDL-cholesterol) of diabetes and oxidative stress: knowing the links

, 2022
Shreelaxmi V. Hegde, Prabha Adhikari, Shashidhar Kotian, Poornima Manjrekar, Rajeshwari Shastry, Vivian D’Souza   +5 more
openalex   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

High-capacity selective uptake of cholesteryl ester from native LDL during macrophage foam cell formation

Journal of Lipid Research, 2012
Macrophage foam cells are a defining pathologic feature of atherosclerotic lesions. Recent studies have demonstrated that at high concentrations associated with hypercholesterolemia, native LDL induces macrophage lipid accumulation.
Jason M. Meyer, Ailing Ji, Lei Cai, Deneys R. van der Westhuyzen   +3 more
doaj   +1 more source

Carotid intima media thickness and low high-density lipoprotein (HDL) in South Asian immigrants: could dysfunctional HDL be the missing link? [PDF]

, 2014
IntroductionSouth Asian immigrants (SAIs) in the US exhibit higher prevalence of coronary artery disease (CAD) and its risk factors compared with other ethnic populations.
Dodani, Sunita, Dong, Lei, Guirgis, Faheem W, Reddy, Srinivasa T   +3 more
core   +2 more sources

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

Bempedoic Acid: A New Tool for LDL-Cholesterol Control in Patients with Coronary Artery Disease [PDF]

, 2022
Claudio Bilato, Giorgio Sesti, Maurizio Averna   +2 more
openalex   +1 more source

A Meta-Analysis of 46 Studies Identified by the FDA Demonstrates that Soy Protein Decreases Circulating LDL and Total Cholesterol Concentrations in Adults.

Journal of NutriLife, 2019
BACKGROUND Certain plant foods (nuts and soy protein) and food components (viscous fibers and plant sterols) have been permitted by the FDA to carry a heart health claim based on their cholesterol-lowering ability.
Sonia Blanco Mejia, M. Messina, Siying S. Li, E. Viguiliouk, L. Chiavaroli, T. Khan, K. Srichaikul, A. Mirrahimi, J. Sievenpiper, P. Kris-Etherton, D. Jenkins   +10 more
semanticscholar   +1 more source