Screening Signals of Reference-Defined Metabolic Syndrome Using HbA1c and LDL Cholesterol: An Explainable Machine Learning Study. [PDF]
Demir O.
europepmc +1 more source
Inclisiran-induced LDL-cholesterol reduction with and without concomitant statin therapy: a real-world analysis. [PDF]
Seidel M +6 more
europepmc +1 more source
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang +11 more
wiley +1 more source
Comparative Evaluation of Machine Learning Models and Conventional Formulas for LDL Cholesterol Estimation. [PDF]
Orhan B +3 more
europepmc +1 more source
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto +9 more
wiley +1 more source
Effect of pemafibrate on LDL-cholesterol properties in type 2 diabetes and hypertriglyceridemia by lipid management status: PARM-T2D post hoc analysis. [PDF]
Kitsunai H +8 more
europepmc +1 more source
Metrnl: A Novel Therapeutic Target in Atherosclerosis
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley +1 more source
The Complex Relationship Between HDL/LDL Cholesterol, Stroke and Cardiovascular Disease. [PDF]
Parker M +4 more
europepmc +1 more source
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
Higher Small Dense LDL Cholesterol to LDL Cholesterol Ratio is Associated with Glomerular Hyperfiltration in Adults without Diabetes. [PDF]
Morimoto N +6 more
europepmc +1 more source

