Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen +7 more
wiley +1 more source
LDL cholesterol and clinical outcomes in heart failure with reduced ejection fraction a competing risk analysis. [PDF]
Wang Q +7 more
europepmc +1 more source
Computer‐Aided Functional Oligosaccharide Screening and the Regulatory Role in Lipid Metabolism
ABSTRACT This study investigated the lipid‐lowering effects and intervention mechanisms of structurally diverse functional oligosaccharides on non‐alcoholic fatty liver disease (NAFLD). By integrating computational tools such as molecular docking and molecular dynamics simulations (MDS), a comprehensive “in silico‐in vitro‐in vivo” tri‐dimensional ...
Rui Jing +3 more
wiley +1 more source
Bundled measurement of LDL-cholesterol, lipoprotein(a), and high sensitivity C-reactive protein across the spectrum of cardiovascular risk. [PDF]
Razavi AC +3 more
europepmc +1 more source
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi +4 more
wiley +1 more source
ABCC4 impairs the clearance of plasma LDL cholesterol through suppressing LDLR expression in the liver. [PDF]
Chen J +18 more
europepmc +1 more source
Phytosterol Enriched Food Supplements for Plasma LDL-Cholesterol Lowering: Yes or No?
Frans Stellaard, Dieter Lütjohann
openalex +2 more sources
7-016 Efficacy of Inclisiran in patients post myocardial infarction with high total cholesterol and LDL levels and intolerance to statins [PDF]
Yi Lung Gan +5 more
openalex +1 more source

