Results 131 to 140 of about 37,789 (262)
Oral Diseases, EarlyView.ABSTRACT Aim The objective of this study was to investigate the global profile of plasmatic proteins of individuals affected simultaneously or not by type 2 diabetes mellitus (T2DM, well/poorly‐controlled), Dyslipidemia (DL), and Periodontitis (P). Methods Besides periodontal examination, plasma was collected for glycemic, and lipid analyses from 150 ...
François Isnaldo Dias Caldeira +7 more
wiley +1 more source
Nicotine induces LDLR expression in OSCC.
, 2013 Ca9-22 cells were stimulated with various concentrations of nicotine for 3 h (A) or with 100 μM of nicotine for various durations (B). (C) HSC3 cells were stimulated with or without 100 μM of nicotine for 3 and 6 h . (D) Ca9-22 cells were stimulated with
Koichi Ito (497958) +10 more
core +1 more source
Decoding host–microbial dynamics in peri‐implantitis: Ecosystem‐specific experimental models
Periodontology 2000, EarlyView.Abstract Background Peri‐implantitis is an inflammatory disease arising within a unique host–microbial–biomaterial ecosystem. Unlike periodontitis, peri‐implant tissues lack a periodontal ligament and epithelial junction integrity and interface with metal oxides on titanium surfaces.
Georgios A. Kotsakis +5 more
wiley +1 more source
Veterinary and Comparative Oncology, EarlyView.ABSTRACT Tumour cells commonly exhibit aerobic glycolysis and produce lactate despite oxygen availability. Lactate dehydrogenase (LDH) catalyses pyruvate‐lactate interconversion and regulates intracellular lactate levels. Endothelial cells also depend on glycolysis for ATP production, which prompted us to investigate LDH in canine hemangiosarcoma (HSA),
Tamami Suzuki +6 more
wiley +1 more source
Increased expression of LDLr and LRP1.
, 2013 (A) RT-QPCR analyses of mRNA expression of LDLr, VLDLr and SR-B1, n = 4 per group. (B) mRNA expression of VLDLr in HL-1 cells incubated in hypoxia for 0.5, 1, 6 and 24 h (n = 3). (C) Representative immunoblots of LDLr and LRP1.
Christina Drevinge (407558) +8 more
core +1 more source
Experimental Physiology, EarlyView.Abstract Pregnancy requires the coordinated maternal reorganization of lipid and endocrine pathways to sustain fetal growth and anticipate neonatal nutrition. Leptin, produced by adipose tissue and the placenta, acts as an integrative signal linking maternal energy status with trophoblast function and vascular adaptation, while cholesterol provides ...
Julio Flores +4 more
wiley +1 more source
HepG2 cells clear LPS in LDLR-dependent manner.
, 2016 (A) The LDLR specific and scrambled siRNAs were reversely transfected into HepG2 cells. After 24, 48 and 72 hrs, the cells were detached and stained with LDLR-PE conjugated antibody. The LDLR levels were analyzed by flow cytometry.
James A. Russell (484683) +6 more
core +1 more source
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
The Journal of Physiology, EarlyView.Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.Adipocyte‐derived KIF13B promotes LRP1 localization and nuclear LRP1–PPARγ transcriptional activity, thereby enhancing adipogenic gene expression, lipid accumulation, and obesity‐associated metabolic dysfunction. Adipocyte‐specific Kif13b deletion disrupts this LRP1/PPARγ axis, suppresses adipogenic programming, reduces adipose expansion, and protects ...
Guolin Miao +19 more
wiley +1 more source
, 2014 (A) For analysis of FITC-LDL binding, CHO-ldlA7 transfected cells with different LDLR variants were incubated for 4 h at 4°C with 20 µg/mL of FITC-LDL as indicated.
Helena Ostolaza (229309) +5 more
core +1 more source