Results 71 to 80 of about 2,351,452 (290)
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
miR-210 overexpression increases pressure overload-induced cardiac fibrosis
Non-coding RNA ResearchAortic stenosis, a common valvular heart disease, can lead to left ventricular pressure overload, triggering pro-fibrotic responses in the heart. miR-210 is a microRNA that responds to hypoxia and ischemia and plays a role in immune regulation and in ...
G. Zaccagnini +12 more
doaj +1 more source
Acta Scientiarum: Animal Sciences, 2018 This study was developed to evaluate productive efficiency during the lactation period of cows with predominant Nellore genetic composition based on their body size. Cows were divided into the following categories: light (≤ 316 kg), moderate (≥ 317 and ≤
Gustavo Duarte Farias +6 more
doaj +1 more source
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study
Arthritis Care &Research, EarlyView.Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs +15 more
wiley +1 more source
LEVELS OF LEAD AND CADMIUM RESIDUES IN TISSUES OF BOVINE SLAUGHTERED IN PORT-SAID GOVERNORATE
Assiut Veterinary Medical Journal, 2009 Two hundred and ten samples from bovine kidneys, livers, lungs, spleens, mesenteric lymph nodes, muscular portions of diaphragm and brains were collected randomly from 30 fit bovine carcasses for human consumption from Port-Said abattoirs.
H.EL-S.M. FARAG +2 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro +6 more
wiley +1 more source
Cardiology Research and Practice, 2014 Background. Bicuspid aortic valve (BAV) is one of the most common congenital heart disease (0.9%–2%) and is frequently found in the athletes and in the general population.
Laura Stefani +4 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns +2 more
wiley +1 more source