Childhood Lead Exposure in Primary Health Care Settings in Indonesia: A Cross-Sectional Study in Bogor City and Bogor Regency. [PDF]
Suraya A +13 more
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Lead exposure and risk of ADHD and conduct disorders in children: evidence from a retrospective cohort in Philadelphia, PA. [PDF]
Pei X +8 more
europepmc +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Reducing Workers\u2019 Lead Exposure during Water Service Line Removal and Replacement
Workers who replace lead water service lines may be exposed to lead pipes and lead-contaminated soil while removing the old water lines and replacing them with lead-free lines.
core
Waterborne Lead Exposure Induces Hepatic Oxidative Stress and Transcriptomic Responses in Pufferfish (<i>Takifugu obscurus</i>). [PDF]
Fu S, Qian K, Yao T, Lu J, Ye L, Ye J.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Association of occupational lead exposure with erythrocytic parameters and nitric oxide-related metabolites: a case-control study. [PDF]
Gözükara MG +7 more
europepmc +1 more source
Lead Speciation and Occupational Exposure [PDF]
openaire +2 more sources
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source

