Results 191 to 200 of about 3,485,484 (310)

Identifying critical windows of susceptibility to perinatal lead exposure on child serum vaccine antibody levels. [PDF]

Am J Epidemiol
Colicino E, Feiler MO, Austin C, Rosa MJ, McRae N, Quataert SA, Thevenet-Morrison K, Téllez-Rojo MM, Lamadrid-Figueroa H, Tavarez ZQ, Shim YK, Arora M, Wright RO, Jusko TA.   +13 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Lead exposure is associated with increased lead bioaccumulation and a decline in semen quality: a systematic review and meta-analysis. [PDF]

JBRA Assist Reprod
Adisa VI, Ashonibare PJ, Adegbola CA, Akhigbe TM, Kolawole OR, Omole IA, Fidelis FB, Adeogun AE, Oluwole RP, Akorede BA, Ogunkola BD, Adekunle AO, Hassan SA, Mansur SS, Ajeigbe SB, Oyedokun PA, Ashonibare VJ, Adelowo OE, Oyesetan RI, Oladipo AA, Akhigbe RE.   +20 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

From awareness to action: enhancing mothers' knowledge and practices on lead exposure among young children in the Bani-Khaled Village, Minia Governorate. [PDF]

BMC Public Health
Touni MI, Hashem AM, Moustafa MF, Ahmed ES, Mohammed HM, Elsayed EE.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Personalized lead exposure information and preventive behaviors in Ivory Coast: Insights from a pilot study. [PDF]

PLoS One
Gille V, Gubert F, Saint-Macary C, Dos Santos S, Houffoué F, Kouadio H, Marahoua E, Soro P, van Geen A.   +8 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Eliminating lead-exposure in nebulization therapy by lead-free piezoelectric. [PDF]

Nat Commun
Yao FZ, Fan W, Zhang Y, Han B, Feng Z, Chen B, Dou Z, Jiang J, Li Z, Gao H, Wu C, Liang N, Wei Y, Wei Y, Wang K, Ma X, Gong W.   +16 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source