Results 181 to 190 of about 3,479,224 (308)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Lead exposure is associated with increased lead bioaccumulation and a decline in semen quality: a systematic review and meta-analysis. [PDF]

JBRA Assist Reprod
Adisa VI, Ashonibare PJ, Adegbola CA, Akhigbe TM, Kolawole OR, Omole IA, Fidelis FB, Adeogun AE, Oluwole RP, Akorede BA, Ogunkola BD, Adekunle AO, Hassan SA, Mansur SS, Ajeigbe SB, Oyedokun PA, Ashonibare VJ, Adelowo OE, Oyesetan RI, Oladipo AA, Akhigbe RE.   +20 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

From awareness to action: enhancing mothers' knowledge and practices on lead exposure among young children in the Bani-Khaled Village, Minia Governorate. [PDF]

BMC Public Health
Touni MI, Hashem AM, Moustafa MF, Ahmed ES, Mohammed HM, Elsayed EE.   +5 more
europepmc   +1 more source

Lead Speciation and Occupational Exposure [PDF]

Environmental Health Perspectives, 1998
openaire   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Personalized lead exposure information and preventive behaviors in Ivory Coast: Insights from a pilot study. [PDF]

PLoS One
Gille V, Gubert F, Saint-Macary C, Dos Santos S, Houffoué F, Kouadio H, Marahoua E, Soro P, van Geen A.   +8 more
europepmc   +1 more source

Lead exposure.

The Western journal of medicine, 1992
G E, Johnson, G H, Hess
openaire   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Eliminating lead-exposure in nebulization therapy by lead-free piezoelectric. [PDF]

Nat Commun
Yao FZ, Fan W, Zhang Y, Han B, Feng Z, Chen B, Dou Z, Jiang J, Li Z, Gao H, Wu C, Liang N, Wei Y, Wei Y, Wang K, Ma X, Gong W.   +16 more
europepmc   +1 more source