Results 111 to 120 of about 384,964 (298)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
An investigation of end user development success
, 2002 User development of applications provides end users with an alternative to the traditional process of systems development by allowing them to solve job related problems by developing their own software applications.
McGill, Tanya Jane
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Local User-Producer Interaction in Innovation and Export Performance of Firms [PDF]
There is ample evidence that user-producer interaction is an important factor for successful innovations. It is often claimed that user-producer interaction is most effcient in close proximity.
Beise, Marian, Rammer, Christian
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Analysis of Automatic Online Lead User Identification
, 2013 Lead user identification is a systematic approach to uncovering product development opportunities by identifying lead users, individuals or groups actively involved in modifying or developing products for personal benefit.
Pajo, Sanjin +3 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
User participation in the categorisation of the State Library of Queensland digital image collections: characteristics, motivations and experiences [PDF]
, 2012 In 2010, the State Library of Queensland (SLQ) donated their out-of-copyright Queensland images to Wikimedia Commons. One direct effect of publishing the collections at Wikimedia Commons is the ability of general audiences to participate and help the ...
Partridge, Helen L. +3 more
core
Terminals behavior testing research under IPv6 Wi-Fi
Tongxin xuebao, 2014 As lack of essential data,carrier operators are afraid to promote IPv6 in mobile Internet due to they cannot forecast the influence of user experience.The main current mobile terminals behavior under IPv6 Wi-Fi was tested,the key point to impact user ...
Jie ZHANG, Qin ZHAO, Tian-le YANG
doaj +2 more sources