Results 141 to 150 of about 1,264,726 (304)

Medical Education Scholars Program: an approach to development of scholars in education in Tehran University of Medical Sciences

open access: yesAdvances in Medical Education and Practice, 2019
Azadeh Kordestani Moghaddam,1 Azim Mirzazadeh1–31Department of Medical Education, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; 2Department of Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran ...
Kordestani Moghaddam A, Mirzazadeh A
doaj  

A coherent agri-energy policy to foster social inclusion for peasant families: the role of Petrobras on the João Câmara and Ceará-Mirim sites (state of Rio Grande do Norte) [PDF]

open access: yes
This article depicts the improvement in living conditions for those families of peasants (the “landless peasants”) who have benefited from agrarian reform (termed “assentamentos” i.e. homesteads) through the creation of farming cooperatives.
C.M Drouvot, H. Drouvot, P.M Perluss
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Fusion Center Leaders Program

open access: yes, 2013
The Naval Postgraduate School Center for Homeland Defense and Security offers a Fusion Center Leaders Program (FCLP) built upon guidance from the National Fusion Center Management Group comprising state and local partners, Office of the Director of National Intelligence (ODNI), Department of Homeland Security (DHS), and Department of Justice (DOJ ...
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Global Health Means Listening by Raymond Downing, Manqa, 2018

open access: yesChristian Journal for Global Health, 2019
Adamu Addissie
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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