Results 241 to 250 of about 596,747 (294)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Leadership as Action: Empowering Innovation, Influence, and Growth in Therapeutic Massage and Bodywork. [PDF]
Baskwill A.
europepmc +1 more source
Project GLOBE: Global Leadership and Organizational Behavior Education
Marcus W. Dickson +3 more
openalex +1 more source
Service quality and leadership in public preschool education in Malaysia
Fathilah Ismail
openalex +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Determinants and outcomes of advanced practice nurses' leadership behaviours: an AI-aided mixed-methods systematic review protocol. [PDF]
Put V +4 more
europepmc +1 more source
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
The relationship between inclusive leadership in sustainable education and teachers' subjective wellbeing in Türkiye: the mediating role of affective commitment. [PDF]
Çevik MN.
europepmc +1 more source

