Results 251 to 260 of about 314,600 (300)

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang   +9 more
wiley   +1 more source

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

open access: yesAdvanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia   +15 more
wiley   +1 more source

Influence of plant spacing and deblossoming on agromorphological and physiological traits of zombi pea. [PDF]

open access: yesSci Rep
Priyadarsini S   +6 more
europepmc   +1 more source
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Oregon ‘Pinot noir’ grape anthocyanin enhancement by early leaf removal

Food Chemistry, 2013
Complete cluster zone leaf removal of 'Pinot noir' was initiated at three separate pre-véraison growth stages (bloom, grain-pea size, and bunch closure) and maintained leaf free until harvest, for four growing seasons (2008-2011). Fruit anthocyanin composition was examined at harvest for the last two vintages (2010 and 2011) and compared to a control ...
Jungmin, Lee, Patricia A, Skinkis
openaire   +4 more sources

Impact of girdling and leaf removal on Alhagi sparsifolia leaf senescence

Plant Growth Regulation, 2015
Leaf senescence can be described as the dismantling of cellular components during the terminal stage in the development of plant organs and tissues. In order to determine the leaf senescence process when stem girdling and leaf removal both exist. An experiment was carried out in Alhagi sparsifolia, which grew in the Cele oasis-desert transitional zone ...
Gang-Liang Tang   +3 more
openaire   +1 more source

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