Results 41 to 50 of about 228,508 (283)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Carbon leakage: an overview. CEPS Special Report No. 79, 6 December 2013 [PDF]

, 2013
Carbon leakage is central to the discussion on climate policy, given the confluence of issues that are currently being debated, including the 2030 Energy and Climate Framework and the review of the EU carbon leakage list by 2014.
Roth, Susanna, Marcu, Andrei, Egenhofer, Christian., Stoefs, Wijnand   +3 more
core  

Numerical Analysis of Operating Characteristics of Frequency-dividing Disconnectors for Distribution Line Surge Arresters

Zhongguo dianli, 2022
In order to reduce the workload of the operation and maintenance of distribution line arresters, this paper designs a frequency-dividing disconnector using double sphere gaps based on the inverse time principle, which can reliably shunt high and low ...
Wei LI, Tingfang YANG, Lei ZHANG, Zhiyong LIU, Cheng ZENG   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Analytical Modeling of Slot Leakage Inductance for Hairpin Windings

Machines
With the increasing demand for higher efficiency and power density, innovative winding techniques have become crucial in modern electric machines. Hairpin windings are increasingly used in electric machines, particularly in high-current applications.
Hasnain Nisar, Ali M. Bazzi
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

On the Influence of Increased Stator Leakage Inductance in Single Tooth Wound Synchronous Reluctance Motors [PDF]

, 2017
IEEE This paper explores the leakage inductance of a single tooth wound synchronous reluctance motor and its influence on motor performance. It is shown that the stator leakage inductance heavily influences the true saliency ratio in synchronous ...
Widmer JD, Donaghy-Spargo CM, Mecrow B
core   +4 more sources

Analytical Selection of Leakage Inductance for Single-Phase Dual Active Bridge Converters

Applied Sciences
The single-phase dual active bridge (DAB) DC/DC converter is a vital component in modern power electronics systems, facilitating efficient bidirectional power transfer between various energy sources and loads. One of the critical aspects in the design of
Hamid Naseem, Jul-Ki Seok
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source